Boster Immunoleader

antibody

Anti-CCR9 Antibody

PA2122

100 ug/vial

200 USD

polyclonal

rabbit

Anti-CCR9 Antibody

PA2122

Polyclonal

Rabbit IgG polyclonal antibody for C-C chemokine receptor type 9(CCR9) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human CCR9(1-17aa MTPTDFTSPIPNMADDY).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

C-C chemokine receptor type 9, also called GPR-9-6 or CDw199, is a protein that in humans is encoded by the CCR9 gene. The protein encoded by this gene is a member of the beta chemoking receptor family. By radiation hybrid analysis and organization of BAC contigs by FISH on combed genomic DNA, the CCR9 gene within the CCR cluster was localized at 3p21.3. It is the receptor for chemokine SCYA25/TECK. This gene subsequently transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection. This gene may play a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract.

1. Eksteen, B., Grant, A. J., Miles, A., Curbishley, S. M., Lalor, P. F., Hubscher, S. G., Briskin, M., Salmon, M., Adams, D. H. Hepatic endothelial CCL25 mediates the recruitment of CCR9+ gut-homing lymphocytes to the liver in primary sclerosing cholangitis. J. Exp. Med. 200: 1511-1517, 2004. 2. Mora, J. R., Bono, M. R., Manjunath, N., Weninger, W., Cavanagh, L. L., Rosemblatt, M., von Andrian, U. H. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 424: 88-93, 2003. 3. Papadakis, K. A., Prehn, J., Nelson, V., Cheng, L., Binder, S. W., Ponath, P. D., Andrew, D. P., Targan, S. R. The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. J. Immun. 165: 5069-5076, 2000. 4. Wendland, M., Czeloth, N., Mach, N., Malissen, B., Kremmer, E., Pabst, O., Forster, R. CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine. Proc. Nat. Acad. Sci. 104: 6347-6352, 2007.

CCR9

C-C chemokine receptor type 9

chemokine(C-C motif) receptor 9

C C chemokine receptor D6 antibody C C chemokine receptor type 9 antibody C C CKR 9 antibody CC Chemokine receptor CCR10 antibody CC CKR 9 antibody CCBP2 antibody CCCKR9 antibody CCR 9 antibody CCR9 antibody CDw199 antibody CDw199 antigen antibody Chemokine(C C motif) receptor 9 antibody Chemokine(C C motif) receptor 9, isoform CRA_a antibody Chemokine(C-C motif) receptor 9 isoform A antibody Chemokine C C motif receptor 9 antibody Chemokine C C receptor 10 antibody Chemokine CC Motif Receptor 9 antibody Chemokine receptor CCR 9 antibody Chemokine receptor CCR9 antibody Chemokine-binding protein D6 antibody Cmkbr10 antibody CMKBR9 antibody G protein coupled receptor 28 antibody GPR 28 antibody GPR 9 6 antibody GPR28 antibody GPR96 antibody OTTHUMP00000164653 antibody OTTHUMP00000164654 antibody

P51686