Anti-FMO5 Antibody | Boster Immunoleader PA2108 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-FMO5 Antibody

catalog :

PA2108

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-FMO5 Antibody

Catalog Number :

PA2108

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Dimethylaniline monooxygenase[N-oxide-forming] 5(FMO5) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human FMO5(77-90aa DHYPNFMHNAQVLE), different from the related rat sequence by one amino acid, and different from the related mouse sequence by two amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Dimethylaniline monooxygenase[N-oxide-forming] 5 also known as FMO 5 is an enzyme that in humans is encoded by the FMO5 gene. By fluorescence in situ hybridization, this gene was assigned to human chromosome 1q21.1. FMO5 is not an efficient drug-metabolizing enzyme and that it may have an alternative physiologic role. FMO5 transcripts play an important role in progesterone-regulated in breast cancer cells specifically under the control of the progesterone receptor B-isoform.

Reference :

1. Gelb, B. D., Zhang, J., Cotter, P. D., Gershin, I. F., Desnick, R. J. Physical mapping of the human connexin 40 (GJA5), flavin-containing monooxygenase 5, and natriuretic peptide receptor A genes on 1q21. Genomics 39: 409-411, 1997. 2. Miller, M. M., James, R. A., Richer, J. K., Gordon, D. F., Wood, W. M., Horwitz, K. B.Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity. J. Clin. Endocr. Metab. 82: 2956-2961, 1997. 3. Overby, L. H., Buckpitt, A. R., Lawton, M. P., Atta-Asafo-Adjei, E., Schulze, J., Philpot, R. M. Characterization of flavin-containing monooxygenase 5(FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog. Arch. Biochem. Biophys. 317: 275-284, 1995.

Gene Name :

FMO5

Protein Name :

Dimethylaniline monooxygenase[N-oxide-forming] 5

Gene Full Name :

flavin containing monooxygenase 5

Synonyms :

Dimethylaniline monooxygenase[N oxide forming] 5 antibody Dimethylaniline monooxygenase[N-oxide-forming] 5 antibody Dimethylaniline oxidase 5 antibody FMO 5 antibody FMO5 antibody FMO5_HUMAN antibody Hepatic flavin containing monooxygenase 5 antibody Hepatic flavin-containing monooxygenase 5 antibody

Uniprot ID :

P49326

more info or order :

Boster Immunoleader product webpage