Anti-Aquaporin 6 Antibody | Boster Immunoleader PA2092 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Aquaporin 6 Antibody

catalog :

PA2092

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Aquaporin 6 Antibody

Catalog Number :

PA2092

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Aquaporin-6(AQP6) detection. Tested with WB, IHC-P in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6(264-282aa EPLKKESQPGSGAVEMESV).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins(AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date(AQPs 0-6), genes encoding the four most closely related aquaporins(AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.

Reference :

1. "Entrez Gene: Aquaporin 6, kidney specific". Retrieved 2012-04-10 2. Ma, T., Yang, B., Umenishi, F., Verkman, A. S. Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. Genomics 43: 387-389, 1997. 3. Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., Yasui, M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc. Nat. Acad. Sci. 102: 2192-2197, 2005.

Gene Name :

AQP6

Protein Name :

Aquaporin-6

Gene Full Name :

aquaporin 6, kidney specific

Synonyms :

AQP-6 antibody AQP2L antibody Aqp6 antibody AQP6_HUMAN antibody Aquaporin 2 like antibody aquaporin 2 like kidney specific antibody aquaporin 2-like kidney specific antibody Aquaporin 6 antibody Aquaporin 6 kidney specific antibody Aquaporin-2-like antibody Aquaporin-6 antibody Aquaporin-6 kidney specific antibody hKID antibody Human kidney water channel(hKID) mRNA, complete cds antibody KID antibody Kidney-specific aquaporin antibody

Uniprot ID :

Q13520

more info or order :

Boster Immunoleader product webpage