Boster Immunoleader

antibody

Anti-VE Cadherin Antibody

PA2079

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

western blot, immunohistochemistry - paraffin section

Anti-VE Cadherin Antibody

PA2079

Polyclonal

Rabbit IgG polyclonal antibody for Cadherin-5(CDH5) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human VE Cadherin(766-784aa RFKMLAELYGSDPREELLY), different from the related mouse and rat sequences by three amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

CDH5(Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al.(1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.

1. Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L. D., Buchberg, A. M., Dejana, E. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Genomics 32: 21-28, 1996. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

CDH5

Cadherin-5

cadherin 5, type 2(vascular endothelium)

7B 4 antibody 7B4 antibody 7B4 antigen antibody CADH5_HUMAN antibody Cadherin 5 antibody Cadherin 5 type 2 antibody Cadherin 5, type 2(vascular endothelium) antibody Cadherin 5, type 2, VE cadherin(vascular epithelium) antibody cadherin, vascular endothelial antibody cadherin, vascular endothelial, 1 antibody Cadherin-5 antibody Cadherin5 antibody CD 144 antibody CD144 antibody CD144 antigen antibody CDH 5 antibody CDH5 antibody CDH5 protein antibody Endothelial specific cadherin antibody FLJ17376 antibody OTTHUMP00000174777 antibody Vascular endothelial cadherin antibody Vascular epithelium cadherin antibody VE Cad antibody VE-cadherin antibody VEC antibody

P33151