Boster Immunoleader

antibody

Anti-ADAMTS1 Antibody

PA2071

100 ug/vial

200 USD

polyclonal

rabbit

mouse, rat

Anti-ADAMTS1 Antibody

PA2071

Polyclonal

Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 1(ADAMTS1) detection. Tested with WB in Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: rat Predicted to work with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of mouse ADAMTS1(956-968aa KHYIDFCTLTQCS), different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

ADAMTS1(A Disintegrin-Like and Metalloproteinase with Thrombospondin Type 1 Motif, 1), also known as METH1, is an enzyme that in humans is encoded by the ADAMTS1 gene. ADAMTS is a family of proteins believed to be anchored to the extracellular matrix(ECM) through interactions with aggregan or other matrix components by one or more thrombospondin type 1 motifs. Scott(2000) mapped the ADAMTS1 gene to 21q21.2 based on sequence similarity between the ADAMTS1 sequence and a chromosome 21q21.2 clone. Kuno et al.(1997) found that mouse Adamts1 expression could be induced in vitro in colon adenocarcinoma cells by stimulation with the inflammatory cytokine interleukin 1-alpha, or in vivo in kidney and heart by intravenous administration of lipopolysaccharide. Vazquez et al.(1999) determined that ADAMTS1 disrupts angiogenesis in vivo and in vitro more efficiently than ADAMTS8, THBS1, or endostatin.

1. Kuno, K., Kanada, N., Nakashima, E., Fujiki, F., Ichimura, F., Matsushima, K. Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene. J. Biol. Chem. 272: 556-562, 1997. 2. Scott, A. F. Personal Communication. Baltimore, Md. 9/18/2000. 3. Vazquez, F., Hastings, G., Ortega, M.-A., Lane, T. F., Oikemus, S., Lombardo, M., Iruela-Arispe, M. L. METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity. J. Biol. Chem. 274: 23349-23357, 1999.

ADAMTS1

A disintegrin and metalloproteinase with thrombospondin motifs 1

ADAM metallopeptidase with thrombospondin type 1 motif, 1

A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody A disintegrin like and metalloprotease with thrombospondin type 1 motif 1 antibody A disintegrin-like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 1 antibody ADAM metallopeptidase with thrombospondin type 1 motif 1 antibody ADAM TS 1 antibody ADAM TS1 antibody ADAM-TS 1 antibody ADAM-TS1 antibody ADAMTS 1 antibody ADAMTS antibody ADAMTS-1 antibody Adamts1 antibody ATS1_HUMAN antibody C3 C5 antibody KIAA1346 antibody KIAA1346, antibody METH 1 antibody METH-1 antibody METH1 antibody

P97857