Anti-ABI2 Antibody | Boster Immunoleader PA2068 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-ABI2 Antibody

catalog :

PA2068

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

publications citing this reagent :

Cui M, Yu W, Dong J, Chen J, Zhang X, Liu Y. Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma. Med Oncol. 2010;27:632-9 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-ABI2 Antibody

Catalog Number :

PA2068

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Abl interactor 2(ABI2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2(158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

ABI2(ABL Interactor 2), is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the ABI2 gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein; a central serine-rich region; 3 PEST sequences, which are implicated in susceptibility to protein degradation; several proline-rich stretches; and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.

Reference :

1. Dai, Z., Pendergast, A. M. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes Dev. 9: 2569-2582, 1995. 2. Machado, R. D., Pauciulo, M. W., Fretwell, N., Veal, C., Thomson, J. R., Guell, C. V., Aldred, M., Brannon, C. A., the International PPH Consortium, Trembath, R. C., Nichols, W. C. A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. Genomics 68: 220-228, 2000.

Gene Name :

ABI2

Protein Name :

Abl interactor 2

Gene Full Name :

abl-interactor 2

Synonyms :

Abelson interactor 2 antibody ABI 2 antibody ABI2B antibody Abl binding protein 3 antibody Abl interacting protein 1(SH3 containing protein) antibody Abl interactor 2 antibody Abl interactor protein 2b antibody AblBP3 antibody AIP 1 antibody Arg binding protein 1 antibody Arg protein tyrosine kinase binding protein antibody ArgBP1 antibody ARGBPIA antibody ArgBPIB antibody OTTHUMP00000163783 antibody OTTHUMP00000163784 antibody OTTHUMP00000206182 antibody OTTHUMP00000206183 antibody OTTHUMP00000206184 antibody OTTHUMP00000206185 antibody SSH3BP2 antibody

Uniprot ID :

Q9NYB9

more info or order :

Boster Immunoleader product webpage