Anti-ABCG4 Antibody | Boster Immunoleader PA2067 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-ABCG4 Antibody

catalog :

PA2067

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-ABCG4 Antibody

Catalog Number :

PA2067

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 4(ABCG4) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse, rat Predicted to work with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human ABCG4(327-341aa AVQNGLCAMAEKKSS), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

ABCG4(ATP-Binding Cassette, Subfamily G, Member 4), is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette(ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al.(2001) mapped the ABCG4 gene to chromosome 11q23.3. Engel et al.(2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.

Reference :

1. Annilo, T., Tammur, J., Hutchinson, A., Rzhetsky, A., Dean, M., Allikmets, R. Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4. Cytogenet. Cell Genet. 94: 196-201, 2001. 2. Engel, T., Lorkowski, S., Lueken, A., Rust, S., Schluter, B., Berger, G., Cullen, P., Assmann, G. The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages. Biochem. Biophys. Res. Commun. 288: 483-488, 2001. 3. Yoshikawa, M., Yabuuchi, H., Kuroiwa, A., Ikegami, Y., Sai, Y., Tamai, I., Tsuji, A., Matsuda, Y., Yoshida, H., Ishikawa, T. Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4. Gene 293: 67-75, 2002.

Gene Name :

ABCG4

Protein Name :

ATP-binding cassette sub-family G member 4

Gene Full Name :

ATP-binding cassette, sub-family G(WHITE), member 4

Synonyms :

ABCG 4 antibody ATP binding cassette subfamily G member 4 antibody ATP-binding cassette, sub-family G(WHITE), member 4 antibody Putative ABC transporter antibody WHITE 2 antibody WHITE2 antibody

Uniprot ID :

Q9H172

more info or order :

Boster Immunoleader product webpage