Boster Immunoleader

antibody

Anti-Factor VIII Antibody

PA2061

100 ug/vial

200 USD

polyclonal

rabbit

Anti-Factor VIII Antibody

PA2061

Polyclonal

Rabbit IgG polyclonal antibody for Coagulation factor VIII(F8) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence in the middle region of human Factor VIII(1264-1278aa APVLQDFRSLNDSTN).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Coagulation Factor VIII(FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor(AHF). By in situ hybridization, Tantravahi et al.(1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located. The F8 gene encodes coagulation factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the factor IXa-dependent activation of factor X(F10). Factor VIII is activated proteolytically by a variety of coagulation enzymes, including thrombin(F2). Factor VIII is tightly associated in the blood with von Willebrand factor(VWF), which serves as a protective carrier protein for factor VIII(Toole et al., 1984; Hoyer, 1994).

1. Hoyer, L. W. Hemophilia A. New Eng. J. Med. 330: 38-45, 1994. 2. Tantravahi, U., Murty, V. V. V. S., Jhanwar, S. C., Toole, J. J., Woozney, J. M., Chaganti, R. S. K., Latt, S. A. Physical mapping of the factor VIII gene proximal to two polymorphic DNA probes in human chromosome band Xq28: implications for factor VIII gene segregation analysis. Cytogenet. Cell Genet. 42: 75-79, 1986. 3. Toole, J. J., Knopf, J. L., Wozney, J. M., Sultzman, L. A., Buecker, J. L., Pittman, D. D., Kaufman, R. J., Brown, E., Shoemaker, C., Orr, E. C., Amphlett, G. W., Foster, W. B., Coe, M. L., Knutson, G. J., Fass, D. N., Hewick, R. M. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 312: 342-347, 1984.

F8

Coagulation factor VIII

coagulation factor VIII, procoagulant component

Ahf antibody Antihemophilic factor antibody Coagulation factor VIII antibody Coagulation factor VIII associated protein b antibody Coagulation factor VIII isoform b antibody Coagulation factor VIII procoagulent component antibody coagulation factor VIII, procoagulant component antibody Coagulation factor VIIIc antibody Dna segment on chromosome x unique 1253 expressed sequence antibody Dxs1253e antibody F8 antibody F8 protein antibody F8b antibody F8c antibody FA8_HUMAN antibody Factor VIII F8b antibody Factor VIIIa light chain antibody FactorVIII antibody FVIII antibody Hema antibody Hema coagulation factor VIIIc procoagulent component antibody Hemophilia a antibody Hemophilia classic antibody Hemophilia, classic antibody OTTHUMP00000061446 antibody OTTHUMP00000196174 antibody Procoagulant component antibody

P00451