Boster Immunoleader

antibody

Anti-p63 Antibody

PA2056

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

western blot, immunocytochemistry, immunohistochemistry - paraffin section

Anti-p63 Antibody

PA2056

Polyclonal

Rabbit IgG polyclonal antibody for Tumor protein 63(TP63) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB,IHC-P,ICC

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Concentration: 0.5-1μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Concentration: 0.5-1μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human p63(664-680aa DMDARRNKQQRIKEEGE), different from the related rat and mouse sequences by one amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and ICC.

TP63(Tumor Protein p63), also known as KET, is a protein that in humans is encoded by the TP63 gene. Yang et al.(1998) described the cloning of tumor protein p63, which shows strong homology to the tumor suppressor p53 and the p53-related protein p73. By fluorescence in situ hybridization, Yang et al.(1998) localized the human TP63 gene to chromosome 3q27-q29. Hibi et al.(2000) stated that p53 homologs known variously as p40, p51, p63, and p73L(Trink et al., 1998, Yang et al., 1998, Osada et al., 1998, Senoo et al., 1998) are isoforms of the same gene, which Hibi et al.(2000) referred to as AIS for amplified in squamous cell carcinoma.

1. Hibi, K., Trink, B., Patturajan, M., Westra, W. H., Caballero, O. L., Hill, D. E., Ratovitski, E. A., Jen, J., Sidransky, D. AIS is an oncogene amplified in squamous cell carcinoma. Proc. Nat. Acad. Sci. 97: 5462-5467, 2000. 2. Osada, M., Ohba, M., Kawahara, C., Ishioka, C., Kanamaru, R., Katoh, I., Ikawa, Y., Nimura, Y., Nakagawara, A., Obinata, M., Ikawa, S. Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nature Med. 4: 839-843, 1998. 3. Senoo, M., Seki, N., Ohira, M., Sugano, S., Watanabe, M., Inuzuka, S., Okamoto, T., Tachibana, M., Tanaka, T., Shinkai, Y., Kato, H. A second p53-related protein, p73L, with high homology to p73. Biochem. Biophys. Res. Commun. 248: 603-607, 1998. Note: Erratum: Biochem. Biophys. Res. Commun. 250: 536 only, 1998. 4. Trink, B., Okami, K., Wu, L., Sriuranpong, V., Jen, J., Sidransky, D. A new human p53 homologue. (Letter) Nature Med. 4: 747-748, 1998. 5. Yang, A., Kaghad, M., Wang, Y., Gillett, E., Fleming, M. D., Dotsch, V., Andrews, N. C., Caput, D., McKeon, F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Molec. Cell 2: 305-316, 1998.

TP63

Tumor protein 63

tumor protein p63

AIS antibody Amplified in squamous cell carcinoma antibody B(p51A) antibody B(p51B) antibody Chronic ulcerative stomatitis protein antibody CUSP antibody DN p63 alpha 1 antibody DNp63 antibody EEC3 antibody id:ibd3516 antibody Keratinocyte transcription factor antibody Keratinocyte transcription factor KET antibody KET antibody LMS antibody MGC115972 antibody MGC192897 antibody NBP antibody OFC8 antibody OTTHUMP00000209732 antibody OTTHUMP00000209733 antibody OTTHUMP00000209734 antibody OTTHUMP00000209735 antibody OTTHUMP00000209737 antibody OTTHUMP00000209738 antibody OTTHUMP00000209739 antibody OTTHUMP00000209740 antibody OTTHUMP00000209741 antibody OTTHUMP00000209742 antibody OTTHUMP00000209743 antibody OTTHUMP00000209744 antibody p40 antibody p51 antibody P51/P63 antibody p53 like transcription factor antibody p53 related protein antibody p53-related protein p63 antibody p53CP antibody p63 antibody P63_HUMAN antibody P73 antibody p73H antibody p73L antibody RHS antibody SHFM4 antibody TAp63alpha antibody TP53CP antibody TP53L antibody TP63 antibody TP73 antibody TP73L antibody Transformation related protein 63 antibody Transformation-related protein 63 antibody Trp53rp1 antibody Trp63 antibody Tumor protein 63 antibody tumor protein 63 kDa with strong homology to p53 antibody Tumor protein p53-competing protein antibody Tumor protein p53-like antibody tumor protein p63 antibody Tumor protein p63 deltaN isoform delta antibody Tumor protein p73 antibody tumor protein p73-like antibody

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