product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-CXCR5 Antibody
catalog :
PA2021
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
product information
Product Name :
Anti-CXCR5 Antibody
Catalog Number :
PA2021
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 5(CXCR5) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, rat Predicted to work with: mouse
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human CXCR5(358-372aa SSLSESENATSLTTF), identical to the related rat and mouse sequences.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
CXCR5(Chemokine CXC Motif Receptor 5), also known as BLR1, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13(also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).
Reference :
1. Allen, C. D. C., Ansel, K. M., Low, C., Lesley, R., Tamamura, H., Fujii, N., Cyster, J. G. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nature Immun. 5: 943-952, 2004. 2. Chan, C.-C., Shen, D., Hackett, J. J., Buggage, R. R., Tuaillon, N. Expression of chemokine receptors, CXCR4 and CXCR5, and chemokines, BLC and SDF-1, in the eyes of patients with primary intraocular lymphoma. Ophthalmology 110: 421-426, 2003. 3. Reif, K., Ekland, E. H., Ohl, L., Nakano, H., Lipp, M., Forster, R., Cyster, J. G. Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position. Nature 416: 94-99, 2002.
Gene Name :
CXCR5
Protein Name :
C-X-C chemokine receptor type 5
Gene Full Name :
chemokine(C-X-C motif) receptor 5
Synonyms :
BLR 1 antibody BLR1 antibody Burkitt lymphoma receptor 1 antibody Burkitt lymphoma receptor 1 GTP binding protein antibody C X C chemokine receptor type 5 antibody C-X-C chemokine receptor type 5 antibody CD 185 antibody CD185 antibody CD185 antigen antibody Chemokine C X C motif receptor 5 antibody Chemokine CXC motif receptor 5 antibody Chemokine receptor 5 antibody CXC chemokine receptor type 5 antibody CXC R5 antibody CXC-R5 antibody CXCR 5 antibody CXCR-5 antibody Cxcr5 antibody CXCR5_HUMAN antibody MDR 15 antibody MDR-15 antibody MDR15 antibody MGC117347 antibody Monocyte derived receptor 15 antibody Monocyte-derived receptor 15 antibody
Uniprot ID :
P32302
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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