Anti-TRAF3 Antibody | Boster Immunoleader PA2008 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TRAF3 Antibody

catalog :

PA2008

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-TRAF3 Antibody

Catalog Number :

PA2008

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for TNF receptor-associated factor 3(TRAF3) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human Predicted to work with: mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Notes :

WB: The detection limit for TRAF3 is approximately 0.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human TRAF3(387-403aa RHDQMLSVHDIRLADMD), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

TRAF3(TNF Receptor-Associated Factor 3), also called LAP1, CAP1, CRAF1 or CD40BP, is a protein that in humans is encoded by the TRAF3 gene. The protein encoded by this gene is a member of the TNF receptor(TNFR) associated factor(TRAF) protein family. Gross(2012) mapped the TRAF3 gene to chromosome 14q32.32 based on an alignment of the TRAF3 sequence with the genomic sequence(GRCh37). Dadgostar et al.(2003) determined that the coiled-coil domain of mouse T3jam interacted with the isoleucine zipper domain of Traf3. Oganesyan et al.(2006) demonstrated that cells lacking TRAF3 are defective in type I interferon responses activated by several different Toll-like receptors.

Reference :

1. Dadgostar, H., Doyle, S. E., Shahangian, A., Garcia, D. E., Cheng, G. T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK. FEBS Lett. 553: 403-407, 2003. 2. Gross, M. B. Personal Communication. Baltimore, Md. 10/5/2012. 3. Oganesyan, G., Saha, S. K., Guo, B., He, J. Q., Shahangian, A., Zarnegar, B., Perry, A., Cheng, G. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 439: 208-211, 2006.

Gene Name :

TRAF3

Protein Name :

TNF receptor-associated factor 3

Gene Full Name :

TNF receptor-associated factor 3

Synonyms :

CAP 1 antibody CAP-1 antibody CAP1 antibody CD40 associated protein 1 antibody CD40 binding protein antibody CD40 bp antibody CD40 receptor associated factor 1 antibody CD40 receptor-associated factor 1 antibody CD40-binding protein antibody CD40bp antibody CRAF 1 antibody CRAF1 antibody IIAE5 antibody LAP 1 antibody LAP1 antibody LMP1 associated protein antibody LMP1-associated protein 1 antibody MIPT3 antibody TNF receptor associated factor 3 antibody TNF receptor-associated factor 3 antibody TRAF 3 antibody Traf3 antibody TRAF3_HUMAN antibody

Uniprot ID :

Q13114

more info or order :

Boster Immunoleader product webpage