Boster Immunoleader

antibody

Anti-DR3 Antibody

PA2004

100 ug/vial

200 USD

polyclonal

rabbit

Anti-DR3 Antibody

PA2004

Polyclonal

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 25(TNFRSF25) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

WB: The detection limit for TNFRSF25 is approximately 3ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human DR3(73-94aa CPQDTFLAWENHHNSECARCQA).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

TNFRSF25(Tumor Necrosis Factor Receptor Superfamily Member 25), also known as LARD, APO3, DR3 or TNFR25, is a protein that in humans is encoded by the TNFRSF25 gene. Members of the mammalian tumor necrosis factor receptor(TNFR) family are cell-surface proteins that interact with a corresponding TNF-related ligand family. By fluorescence in situ hybridization, Marsters et al.(1996) mapped the Apo3 gene to 1p36.3. Marsters et al.(1996) showed that ectopic expression of Apo3 in mammalian cells triggered apoptosis and activated the transcription factor NF-kappa-B. They suggested that, like TNFR1, Apo3 may regulate distinct signaling pathways in different cellular contexts.

1. Borysenko, C. W., Furey, W. F., Blair, H. C. Comparative modeling of TNFRSF25 (DR3) predicts receptor destabilization by a mutation linked to rheumatoid arthritis. Biochem. Biophys. Res. Commun. 328: 794-799, 2005. 2. Fang, L., Adkins, B., Deyev, V., Podack, E. R. Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation. J. Exp. Med. 205: 1037-1048, 2008. 3. Marsters, S. A., Sheridan, J. P., Donahue, C. J., Pitti, R. M., Gray, C. L., Goddard, A. D., Bauer, K. D., Ashkenazi, A. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa-B. Curr. Biol. 6: 1669-1676, 1996.

TNFRSF25

Tumor necrosis factor receptor superfamily member 25

tumor necrosis factor receptor superfamily, member 25

Apo 3 antibody Apo-3 antibody Apo3 antibody Apoptosis inducing receptor AIR antibody Apoptosis inducing receptor antibody Apoptosis mediating receptor antibody Apoptosis mediating receptor DR 3 antibody Apoptosis mediating receptor DR3 antibody Apoptosis mediating receptor TRAMP antibody Apoptosis-inducing receptor AIR antibody Apoptosis-mediating receptor DR3 antibody Apoptosis-mediating receptor TRAMP antibody DDR 3 antibody DDR3 antibody Death domain receptor 3 antibody Death Receptor 3 antibody Death receptor beta antibody DR 3 antibody LARD antibody Lymphocyte associated receptor of death antibody Lymphocyte-associated receptor of death antibody Protein WSL antibody Protein WSL-1 antibody TNFRSF 12 antibody TNFRSF 25 antibody TNFRSF12 antibody TNFRSF25 antibody TNR25_HUMAN antibody TR 3 antibody TR3 antibody TRAMP antibody Translocating chain association membrane protein antibody Tumor necrosis factor receptor superfamily member 12 antibody Tumor necrosis factor receptor superfamily member 25 antibody WSL 1 antibody WSL antibody WSL LR antibody WSL protein antibody WSL1 antibody WSL1 protein antibody WSLLR antibody

Q93038