Boster Immunoleader

antibody

Anti-AREB6 Antibody

PA1986

100 ug/vial

200 USD

polyclonal

rabbit

human, rat

Anti-AREB6 Antibody

PA1986

Polyclonal

Rabbit IgG polyclonal antibody for Zinc finger E-box-binding homeobox 1(ZEB1) detection. Tested with WB in Human;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human Predicted to work with: rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Rat

WB: The detection limit for ZEB1 is approximately 1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human AREB6(108-123aa KDDECESDAENEQNHD), different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

ZEB1(Zinc Finger E Box-Binding Homeobox 1), also called TCF8, NIL2A or DELTA-EF1, is a protein that in humans is encoded by the ZEB1 gene. Fluorescence in situ hybridization localized the ZEB1 gene to chromosome 10p11.2. Krafchak et al.(2005) demonstrated a complex(core plus secondary) binding site for TCF8 in the promoter of the COL4A3 gene, mutant in Alport syndrome and which encodes collagen type IV alpha-3. They detected expression of TCF8 in cornea. Nishimura et al.(2006) found that delta-Ef1 was upregulated during differentiation in a mouse smooth muscle cell(SMC) line.

1. Krafchak, C. M., Pawar, H., Moroi, S. E., Sugar, A., Lichter, P. R., Mackey, D. A., Mian, S., Nairus, T., Elner, V., Schteingart, M. T., Downs, C. A., Kijek, T. G., and 9 others. Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells. Am. J. Hum. Genet. 77: 694-708, 2005. 2. Nishimura, G., Manabe, I., Tsushima, K., Fujiu, K., Oishi, Y., Imai, Y., Maemura, K., Miyagishi, M., Higashi, Y., Kondoh, H., Nagai, R. Delta-EF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev. Cell 11: 93-104, 2006.

ZEB1

Zinc finger E-box-binding homeobox 1

zinc finger E-box binding homeobox 1

AREB 6 antibody BZP antibody Delta crystallin enhancer binding factor 1 antibody DELTA EF1 antibody FECD6 antibody MGC133261 antibody Negative regulator of IL 2 antibody Negative regulator of IL2 antibody NIL 2 A antibody NIL 2 A zinc finger protein antibody NIL 2A antibody NIL-2-A zinc finger protein antibody NIL2A antibody Posterior polymorphous corneal dystrophy 3 antibody PPCD3 antibody Represses interleukin 2 expression antibody TCF 8 antibody TCF-8 antibody TCF8 antibody Transcription factor 8(represses interleukin 2 expression) antibody Transcription factor 8 antibody ZEB 1 antibody ZEB antibody ZEB1 antibody ZEB1_HUMAN antibody ZFHEP antibody ZFHX 1A antibody ZFHX1A antibody Zinc finger E box binding homeobox 1 antibody Zinc finger E-box-binding homeobox 1 antibody Zinc finger homeodomain enhancer binding protein antibody

P37275