Boster Immunoleader

antibody

Anti-TRPV6 Antibody

PA1980

100 ug/vial

200 USD

polyclonal

rabbit

human, rat

info changed 20150327

Anti-TRPV6 Antibody

PA1980

Polyclonal

Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 6(TRPV6) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, mouse, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

WB: The detection limit for TRPV6 is approximately 2.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human TRPV6(18-37aa KFCRWFQRRESWAQSRDEQN), different from the related rat sequence by one amino acid, and from the mouse sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

TRPV6(Transient Receptor Potential Cation Channel Subfamily V Member 6), also known as ECAC2,CAT1 or CATL, a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine. TRPV6 is a member of the Transient receptor potential(TRP) family of membrane proteins. Using FISH, Peng et al.(2000) mapped the TRPV6 gene to chromosome 7q33-q34. Peng et al.(2000) determined that TRPV6 mediates calcium uptake independent of sodium, chloride, and hydrogen; however, calcium influx was higher at alkaline rather than acidic pH. Functional analysis by Peng et al.(2001) indicated that TRPV5 mediates greater calcium uptake than TRPV6. They concluded that TRPV5 and TRPV6 are calcium-selective channels and share a common ancestral gene.

1. Peng, J.-B., Brown, E. M., Hediger, M. A. Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. Genomics 76: 99-109, 2001. 2. Peng, J.-B., Chen, X.-Z., Berger, U. V., Weremowicz, S., Morton, C. C., Vassilev, P. M., Brown, E. M., Hediger, M. A. Human calcium transport protein CaT1. Biochem. Biophys. Res. Commun. 278: 326-332, 2000. 3. Peng, J.-B., Zhuang, L., Berger, U. V., Adam, R. M., Williams, B. J., Brown, E. M., Hediger, M. A., Freeman, M. R. CaT1 expression correlates with tumor grade in prostate cancer. Biochem. Biophys. Res. Commun. 282: 729-734, 2001.

TRPV6

Transient receptor potential cation channel subfamily V member 6

transient receptor potential cation channel, subfamily V, member 6

ABP/ZF antibody ABPZF antibody Alu binding protein with zinc finger domain antibody Calcium channel CaT1 antibody Calcium transport protein 1 antibody CaT L antibody CaT Like antibody CaT-L antibody CaT-like antibody CaT1 antibody ecac antibody ECaC2 antibody Epithelial apical membrane calcium transporter/channel CaT1 antibody Epithelial calcium channel 2 antibody Epithelial calcium channel antibody HSA277909 antibody LP6728 antibody MGC162545 antibody NUDC antibody Transient receptor potential cation channel subfamily V member 6 antibody TrpV6 antibody TRPV6_HUMAN antibody ZFAB antibody

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