Anti-VRL1 Antibody | Boster Immunoleader PA1977 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-VRL1 Antibody

catalog :

PA1977

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-VRL1 Antibody

Catalog Number :

PA1977

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 2(TRPV2) detection. Tested with WB, IHC-P, IHC-F in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P,IHC-F

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Immunohistochemistry(Frozen Section) :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

WB: The detection limit for TRPV2 is approximately 0.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human VRL1(42-624aa QFQGEDRKFAPQIRVNLNYRK).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and IHC(F).

Background :

TRPV2(Transient Receptor Potential Cation Channel Subfamily V Member 2), also known as VRL1, is a protein that, in humans, is encoded by the TRPV1 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52˚C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.

Reference :

1. Caterina, M. J., Rosen, T. A., Tominaga, M., Brake, A. J., Julius, D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398: 436-441, 1999. 2. Iwata, Y., Katanosaka, Y., Arai, Y., Shigekawa, M., Wakabayashi, S. Dominant-negative inhibition of Ca(2+) influx via TRPV2 ameliorates muscular dystrophy in animal models. Hum. Molec. Genet. 18: 824-834, 2009.

Gene Name :

TRPV2

Protein Name :

Transient receptor potential cation channel subfamily V member 2

Gene Full Name :

transient receptor potential cation channel, subfamily V, member 2

Synonyms :

MGC12549 antibody Osm 9 like TRP channel 2 antibody osm-9-like TRP channel 2 antibody OTRPC2 antibody Sac2b antibody Sac2b(gene name) antibody Stretch activated channel 2B antibody Stretch-activated channel 2B antibody Transient receptor potential cation channel subfamily V member 2 antibody TrpV2 antibody TRPV2_HUMAN antibody Vanilloid receptor like protein 1 antibody Vanilloid receptor-like protein 1 antibody VRL 1 antibody VRL antibody VRL-1 antibody VRL1 antibody

Uniprot ID :

Q9Y5S1

more info or order :

Boster Immunoleader product webpage