product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-TNF Receptor II Antibody
catalog :
PA1974
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse, rat
application :
western blot
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product information
Product Name :
Anti-TNF Receptor II Antibody
Catalog Number :
PA1974
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) detection. Tested with WB in Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat
Notes :
WB: The detection limit for TNFRSF1B is approximately 1ng/lane under reducing conditions.
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNF Receptor II(38-55aa YECQISQEYYDRKAQMCC), different from the related rat sequence by three amino acids.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
TNFRSF1B(Tumor Necrosis Factor Receptor Subfamily Member 1B), also known as TNFR2 or TNFBR, is a protein that in humans is encoded by the TNFRSF1B gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1A. By linkage analysis, Santee and Owen Schaub(1996) confirmed the mapping of the TNFR2 gene to 1p36.3-p36.2. TNFBR(TNFR75) is the larger of the 2 TNF receptors. It is present on many cell types, especially those of myeloid origin, and is strongly expressed on stimulated T and B lymphocytes. Beltinger et al.(1996) noted that TNFR2 is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. TNFR2 may act with TNFR1 to kill nonlymphoid cells.
Reference :
1. Beltinger, C. P., White, P. S., Maris, J. M., Sulman, E. P., Jensen, S. J., LePaslier, D., Stallard, B. J., Goeddel, D. V., de Sauvage, F. J., Brodeur, G. M. Physical mapping and genomic structure of the human TNFR2 gene. Genomics 35: 94-100, 1996.
2. Santee, S. M., Owen-Schaub, L. B. Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization. J. Biol. Chem. 271: 21151-21159, 1996.
Gene Name :
TNFRSF1B
Protein Name :
Tumor necrosis factor receptor superfamily member 1B
Gene Full Name :
tumor necrosis factor receptor superfamily, member 1B
Synonyms :
CD 120b antibody CD120b antibody CD120b antigen antibody Etanercept antibody p75 antibody p75TNFR antibody p80 TNF alpha receptor antibody p80 TNF-alpha receptor antibody TBP-2 antibody TBP2 antibody TBPII antibody TNF R II antibody TNF R2 antibody TNF R75 antibody TNF-R2 antibody TNF-RII antibody TNFBR antibody TNFR 2 antibody TNFR-II antibody TNFR2 antibody TNFR75 antibody TNFR80 antibody TNFRII antibody TNFRSF 1B antibody TNFRSF1B antibody TNR1B antibody TNR1B_HUMAN antibody Tumor necrosis factor beta receptor antibody Tumor necrosis factor binding protein 2 antibody Tumor necrosis factor receptor 2 antibody Tumor necrosis factor receptor superfamily member 1B precursor antibody Tumor necrosis factor receptor type II antibody Tumor necrosis factor-binding protein 2 antibody
Uniprot ID :
P25119
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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