Boster Immunoleader

antibody

Anti-LTBR Antibody

PA1968

100 ug/vial

200 USD

polyclonal

rabbit

western blot, immunohistochemistry - paraffin section

Anti-LTBR Antibody

PA1968

Polyclonal

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 3(LTBR) detection. Tested with WB, IHC-P in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

WB: The detection limit for LTBR is approximately 2.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human LTBR(420-435aa ATPSNRGPRNQFITHD).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

LTBR(Lymphotoxin B Receptor), also called TNFCR or LT-BETA-R, is a receptor for lymphotoxin which in humans is encoded by the LTBR gene. By linkage analysis with recombinant inbred mouse strains, Nakamura et al.(1995) demonstrated that the Tnfcr locus is close to the Tnfr1 gene on mouse chromosome 6. Presumably, the human homolog is located on 12p13. Silva-Santos et al.(2005) reported that double-positive T cells regulate the differentiation of early thymocyte progenitors and gamma-delta cells by a mechanism dependent on the transcription factor ROR-gamma-t and the lymphotoxin-beta receptor. Lo et al.(2007) identified lymphotoxin and LIGHT(TNFSF14), tumor necrosis factor cytokine family members that are primarily expressed on lymphocytes, as critical regulators of key enzymes that control lipid metabolism.

1. Lo, J. C., Wang, Y., Tumanov, A. V., Bamji, M., Yao, Z., Reardon, C. A., Getz, G. S., Fu, Y.-X. Lymphotoxin beta receptor-dependent control of lipid homeostasis. Science 316: 285-288, 2007. 2. Nakamura, T., Tashiro, K., Nazarea, M., Nakano, T., Sasayama, S., Honjo, T. The murine lymphotoxin-beta receptor cDNA: isolation by the signal sequence trap and chromosomal mapping. Genomics 30: 312-319, 1995. 3. Silva-Santos, B., Pennington, D. J., Hayday, A. C. Lymphotoxin-mediated regulation of gamma-delta cell differentiation by alpha-beta T cell progenitors. Science 307: 925-928, 2005.

LTBR

Tumor necrosis factor receptor superfamily member 3

lymphotoxin beta receptor(TNFR superfamily, member 3)

CD 18 antibody CD18 antibody CD18 antigen antibody D12S370 antibody LT beta R antibody LTBETAR antibody Ltbr antibody Lymphotoxin B receptor antibody Lymphotoxin beta receptor(TNFR superfamily, member 3) antibody Lymphotoxin beta receptor antibody Lymphotoxin-beta receptor antibody TNF R III antibody TNF-RIII antibody TNFCR antibody TNFR RP antibody TNFR superfamily member 3 antibody TNFR-III antibody TNFR2 RP antibody TNFR2RP antibody TNFR3 antibody TNFRII antibody TNFRRP antibody TNFRSF 3 antibody TNFRSF3 antibody TNR3_HUMAN antibody Tumor necrosis factor C receptor antibody Tumor necrosis factor receptor 2 related protein antibody Tumor necrosis factor receptor 2-related protein antibody Tumor necrosis factor receptor superfamily member 3 antibody Tumor necrosis factor receptor superfamily member 3 precursor antibody Tumor necrosis factor receptor type III antibody

P36941