Boster Immunoleader

antibody

Anti-RIAM Antibody

PA1960

100 ug/vial

200 USD

polyclonal

rabbit

human, rat

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

Anti-RIAM Antibody

PA1960

Polyclonal

Rabbit IgG polyclonal antibody for Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(APBB1IP) detection. Tested with WB, IHC-P, IHC-F, ICC in Human;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB,IHC-P,IHC-F,ICC

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat

Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human; Predicted Species: Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human APBB1IP(647-666aa EQDFMSDLMKALQKKRGNVS), different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P), IHC(F) and ICC.

APBB1IP(APBB1-Interacting Protein), also called RIAM or RARP1, is a protein that in humans is encoded by the APBB1IP gene. By genomic sequence analysis, Lafuente et al.(2004) mapped the RIAM gene to chromosome 10p12.1. Using promoter-reporter gene assays, Inagaki et al.(2003) found that RARP1 suppressed transcription from AP1 and SRE sites, but not CRE sites, in all cell lines examined. The proline-rich regions of RARP1 suppressed AP1 transactivation. Lafuente et al.(2004) found that RIAM interacted with profilin and VASP, molecules that regulate actin dynamics, as well as with RAP1-GTP.

1. Inagaki, T., Suzuki, S., Miyamoto, T., Takeda, T., Yamashita, K., Komatsu, A., Yamauchi, K., Hashizume, K. The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells. J. Biol. Chem. 278: 51685-51692, 2003. 2. Lafuente, E. M., van Puijenbroek, A. A. F. L., Krause, M., Carman, C. V., Freeman, G. J., Berezovskaya, A., Constantine, E., Springer, T. A., Gertler, F. B., Boussiotis, V. A. RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Dev. Cell 7: 585-595, 2004.

APBB1IP

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

amyloid beta(A4) precursor protein-binding, family B, member 1 interacting protein

AB1IP antibody Amyloid beta A4 precursor protein binding family B member 1 interacting protein antibody Amyloid beta precursor protein binding family B member 1 antibody APBB1 interacting protein 1 antibody OTTHUMP00000019344 antibody PREL 1 antibody PREL1 antibody Proline rich EVH1 ligand 1 antibody Proline rich protein 73 antibody Rap1 GTP interacting adapter molecule antibody RAP1 interacting adaptor molecule antibody RARP 1 antibody RARP1 antibody Retinoic acid responsive proline rich protein 1 antibody

Q7Z5R6