Anti-TGM1 Antibody | Boster Immunoleader PA1956 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TGM1 Antibody

catalog :

PA1956

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-TGM1 Antibody

Catalog Number :

PA1956

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Protein-glutamine gamma-glutamyltransferase K(TGM1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human TGM1(498-511aa NSDKVYWQRQDDG), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

TGM1(Transglutaminase1), also known as Transglutaminase, Epidermal Type I or TGK is an enzyme that in humans is encoded by the TGM1 gene. By fluorescence in situ hybridization, Yamanishi et al.(1992) mapped the TGM1 gene to 14q11.2.The TGM1 gene encodes transglutaminase-1, a catalytic membrane-bound enzyme that functions in the formation of the epidermal cornified cell envelope, which acts as a mechanical barrier to protect against water loss and infectious agents.

Reference :

1. Farasat, S., Wei, M.-H., Herman, M., Liewehr, D. J., Steinberg, S. M., Bale, S. J., Fleckman, P., Toro, J. R. Novel transglutaminase-1 mutations and genotype-phenotype investigations of 104 patients with autosomal recessive congenital ichthyosis in the USA. J. Med. Genet. 46: 103-111, 2009. 2. Yamanishi, K., Inazawa, J., Liew, F.-M., Nonomura, K., Ariyama, T., Yasuno, H., Abe, T., Doi, H., Hirano, J., Fukushima, S. Structure of the gene for human transglutaminase 1. J. Biol. Chem. 267: 17858-17863, 1992.

Gene Name :

TGM1

Protein Name :

Protein-glutamine gamma-glutamyltransferase K

Gene Full Name :

transglutaminase 1(K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)

Synonyms :

ARCI1 antibody Epidermal TGase antibody ICR2 antibody KTG antibody LI antibody LI1 antibody Protein glutamine gamma glutamyltransferase K antibody Protein-glutamine gamma-glutamyltransferase K antibody TG(K) antibody TGase 1 antibody TGASE antibody TGase K antibody TGase-1 antibody TGK antibody TGM1 antibody TGM1_HUMAN antibody Transglutaminase 1(K polypeptide epidermal type I, protein glutamine gamma glutamyltransferase) antibody Transglutaminase 1 antibody Transglutaminase K antibody Transglutaminase, keratinocyte antibody Transglutaminase-1 antibody

Uniprot ID :

P22735

more info or order :

Boster Immunoleader product webpage