Anti-CD31 Antibody | Boster Immunoleader PA1950 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD31 Antibody

catalog :

PA1950

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse

application :

western blot

publications citing this reagent :

Chen H, Shi R, Luo B, Yang X, Qiu L, Xiong J, et al. Macrophage peroxisome proliferator-activated receptor γ deficiency delays skin wound healing through impairing apoptotic cell clearance in mice. Cell Death Dis. 2015;6:e1597 pubmed publisher
Yu K, Yang J, Wang F, Chen L, Lu Y, Luo J, et al. Ethanol supports macrophage recruitment and reinforces invasion and migration of lewis lung carcinoma. Alcohol Clin Exp Res. 2014;38:2597-606 pubmed publisher
Zhou S, Yi T, Liu R, Bian C, Qi X, He X, et al. Proteomics identification of annexin A2 as a key mediator in the metastasis and proangiogenesis of endometrial cells in human adenomyosis. Mol Cell Proteomics. 2012;11:M112.017988 pubmed publisher
Ma Y, Sun D, Li J, Yin Z. Transplantation of endothelial progenitor cells alleviates renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction. Life Sci. 2010;86:798-807 pubmed publisher
Xu H, Yin R, Chen L, Siraj S, Huang X, Wang M, et al. An RGD-modified endostatin-derived synthetic peptide shows antitumor activity in vivo. Bioconjug Chem. 2008;19:1980-6 pubmed publisher
Zhang C, Yang F, Zhang X, Wang S, Li M, Lin L, et al. Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells. Br J Pharmacol. 2006;148:741-51 pubmed

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CD31 Antibody

Catalog Number :

PA1950

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Platelet endothelial cell adhesion molecule(PECAM1) detection. Tested with WB in Mouse.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Notes :

WB: The detection limit for PECAM1 is approximately 1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of mouse CD31(547-566aa HNKQASKKQEGQYYCTASNR).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

PECAM-1(Platelet endothelial cell adhesion molecule), also known as cluster of differentiation 31(CD31) is a protein that in human is encoded by the PECAM1 gene found on chromosome 17. PECAM1 is a member of the immunoglobulin(Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. Using a PCR-based analysis of somatic cell hybrids, Gumina et al.(1996) mapped PECAM1 to chromosome 17 in the region 17q23-qter. Several adhesion molecules expressed on platelets and endothelium also localized to 17q. Xie and Muller(1996) mapped the Pecam1 gene to mouse chromosome 6, region F3-G1, by fluorescence in situ hybridization. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions, and PECAM-1 plays a key role in removing aged neutrophils from the body.

Reference :

1. Gumina, R. J., Kirschbaum, N. E., Rao, P. N., vanTuinen, P., Newman, P. J.The human PECAM1 gene maps to 17q23.Genomics 34: 229-232, 1996. 2. Newman, P. J., Berndt, M. C., Gorski, J., White, G. C., II, Lyman, S., Paddock, C., Muller, W. A.PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.Science 247: 1219-1222, 1990. 3. Xie, Y., Muller, W. A.Fluorescence in situ hybridization mapping of the mouse platelet endothelial cell adhesion molecule-1 (PECAM1) to mouse chromosome 6, region F3-G1.Genomics 37: 226-228, 1996.

Gene Name :

PECAM1

Protein Name :

Platelet endothelial cell adhesion molecule

Gene Full Name :

platelet/endothelial cell adhesion molecule 1

Synonyms :

Adhesion molecule antibody CD31 antibody CD31 antigen antibody CD31 EndoCAM antibody Endocam antibody FLJ34100 antibody FLJ58394 antibody GPIIA antibody GPIIA' antibody PECA1 antibody PECA1_HUMAN antibody Pecam 1 antibody PECAM 1 CD31 EndoCAM antibody PECAM antibody PECAM-1 antibody Pecam1 antibody Platelet endothelial cell adhesion molecule antibody Platelet/endothelial cell adhesion molecule 1 antibody Platelet/endothelial cell adhesion molecule antibody

Uniprot ID :

Q08481

more info or order :

Boster Immunoleader product webpage