Boster Immunoleader

antibody

Anti-CD11b Antibody

PA1943

100 ug/vial

200 USD

polyclonal

rabbit

Anti-CD11b Antibody

PA1943

Polyclonal

Rabbit IgG polyclonal antibody for Integrin alpha-M(ITGAM) detection. Tested with WB in Mouse.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

WB: The detection limit for ITGAM is approximately 1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of mouse CD11b(1135-1153aa KRQYKDMMNEAAPQDAPPQ).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

ITGAM(Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT(MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2(alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3(CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated(LFA) antigen type 1(ITGAL), and p150, 95(ITGAX). By in situ hybridization, Corbi et al.(1988) demonstrated that the genes encoding the alpha subunits of LFA1(ITGAL), Mac1, and p150, 95(ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al.(1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al.(2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury(i.e., percutaneous transluminal coronary angioplasty, or PTCA).

1. Callen, D. F., Chen, L. Z., Nancarrow, J., Whitmore, S. A., Apostolou, S., Thompson, A. D., Lane, S. A., Stallings, R. L., Hildebrand, C. E., Harris, P. G., Sutherland, G. R. Current state of the physical map of human chromosome 16. (Abstract) Cytogenet. Cell Genet. 58: 1998 only, 1991. 2. Corbi, A. L., Larson, R. S., Kishimoto, T. K., Springer, T. A., Morton, C. C. Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95: identification of a gene cluster involved in cell adhesion. J. Exp. Med. 167: 1597-1607, 1988. 3. Simon, D. I., Chen, Z., Seifert, P., Edelman, E. R., Ballantyne, C. M., Rogers, C. Decreased neointimal formation in Mac-1 -/- mice reveals a role for inflammation in vascular repair after angioplasty. J. Clin. Invest. 105: 293-300, 2000.

ITGAM

Integrin alpha-M

integrin, alpha M(complement component 3 receptor 3 subunit)

Antigen CD11b p170 antibody CD11 antigen like family member B antibody CD11 antigen-like family member B antibody CD11b antibody CD11b antigen antibody CD11b/CD18 antibody CD49d antibody Cell surface glycoprotein MAC 1 alpha subunit antibody Cell surface glycoprotein MAC-1 subunit alpha antibody Cell Surface Glycoprotein MAC1 Alpha Subunit antibody Complement component 3 receptor 3 subunit antibody Complement Component Receptor 3 Alpha antibody Complement receptor type 3, alpha subunit antibody CR 3 alpha chain antibody CR-3 alpha chain antibody CR3 Alpha Chain antibody CR3 antibody CR3A antibody F730045J24Rik antibody Integrin Alpha M antibody Integrin alpha M chain antibody Integrin alpha M complement component 3 receptor 3 subunit antibody Integrin alpha-M antibody Integrin beta 2 alpha subunit antibody ITAM_HUMAN antibody ITGAM antibody Leukocyte Adhesion Receptor MO1 antibody Ly-40 antibody MAC 1 antibody Mac-1a antibody MAC1 antibody Mac1, alpha subunit antibody MAC1A antibody Macrophage antigen alpha polypeptide antibody MGC117044 antibody Mo1, alpha subunit antibody MO1A antibody Neutrophil adherence receptor alpha M subunit antibody Neutrophil Adherence Receptor antibody SLEB6 antibody

P05555