product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Matrilin 2 Antibody
catalog :
PA1926
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Product Name :
Anti-Matrilin 2 Antibody
Catalog Number :
PA1926
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Matrilin-2(MATN2) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, rat Predicted to work with: mouse
Applications :
WB,IHC-P,IHC-F
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Immunohistochemistry(Frozen Section) :
Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse
Notes :
WB: The detection limit for MATN2 is approximately 1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human Matrilin 2(937-956aa QRLEEMTQRMEALENRLRYR), identical to the related rat sequence and different from the related mouse sequence by one amino acid.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and IHC(F).
Background :
MATN2(Matrilin-2) is a protein that in humans is encoded by the MATN2 gene. This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is though to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. By fluorescence in situ hybridization, Muratoglu et al.(2000) mapped the MATN2 gene to chromosome 8q22. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Reference :
1. Deak, F., Piecha, D., Bachrati, C., Paulsson, M., Kiss, I. Primary structure and expression of matrilin-2, the closest relative of cartilage matrix protein within the von Willebrand factor type A-like module superfamily. J. Biol. Chem. 272: 9268-9274, 1997. 2. Muratoglu, S., Krysan, K., Balazs, M., Sheng, H., Zakany, R., Modis, L., Kiss, I., Deak, F. Primary structure of human matrilin-2, chromosome location of the MATN2 gene and conservation of an AT-AC intron in matrilin genes. Cytogenet. Cell Genet. 90: 323-327, 2000.
Gene Name :
MATN2
Protein Name :
Matrilin-2
Gene Full Name :
matrilin 2
Synonyms :
Crtm2 antibody MATN 2 antibody MATN2 antibody MATN2_HUMAN antibody Matrilin-2 antibody Matrilin2 antibody MGC102477 antibody
Uniprot ID :
O00339
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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