Boster Immunoleader

antibody

Anti-TXNRD2 Antibody

PA1903

100 ug/vial

200 USD

polyclonal

rabbit

human, rat

western blot, immunohistochemistry - paraffin section

Anti-TXNRD2 Antibody

PA1903

Polyclonal

Rabbit IgG polyclonal antibody for Thioredoxin reductase 2, mitochondrial(TXNRD2) detection. Tested with WB, IHC-P in Human;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human TXNRD2(418-434aa RHGQEHVEVYHAHYKPL), different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

TXNRD2(Thioredoxin reductase 2), also known as TRXR2, TR3, SELZ, or TR-BETA, Thioredoxin reductases, are selenocysteine(sec)-containing flavoenzymes that maintain thioredoxins, small proteins that catalyze redox reactions, in the reduced state using the reducing power of NADPH. By STS analysis and genomic sequence analysis, respectively, Miranda-Vizuete et al.(1999) and Sun et al.(1999) mapped the TXNRD2 gene to chromosome 22q11.2. Miranda-Vizuete et al.(1999) mapped the mouse gene to chromosome 16. Gasdaska et al.(1999) showed that TXNRD2 was a thioredoxin reductase that could directly reduce proteins such as insulin.

1. Gasdaska, P. Y., Berggren, M. M., Berry, M. J., Powis, G.Cloning, sequencing, and functional expression of a novel human thioredoxin reductase.FEBS Lett. 442: 105-111, 1999. 2. Miranda-Vizuete, A., Damdimopoulos, A. E., Pedrajas, J. R., Gustafsson, J.-A., Spyrou, G.Human mitochondrial thioredoxin reductase: cDNA cloning, expression, and genomic organization.Europ. J. Biochem. 261: 405-412, 1999. 3. Sun, Q.-A., Wu, Y., Zappacosta, F., Jeang, K.-T., Lee, B. J., Hatfield, D. L., Gladyshev, V. N.Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases.J. Biol. Chem. 274: 24522-24530, 1999.

TXNRD2

Thioredoxin reductase 2, mitochondrial

thioredoxin reductase 2

mitochondrial antibody selenoprotein Z antibody SELZ antibody Thioredoxin reductase 2 antibody Thioredoxin reductase 2 mitochondrial antibody thioredoxin reductase 3 antibody thioredoxin reductase beta antibody Thioredoxin reductase TR3 antibody TR 3 antibody TR antibody TR beta antibody TR-beta antibody TR3 antibody TRXR 2 antibody TRXR2 antibody TRXR2_HUMAN antibody TXNRD 2 antibody Txnrd2 antibody

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