product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-ROR1 Antibody
catalog :
PA1862
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry - paraffin section
product information
Product Name :
Anti-ROR1 Antibody
Catalog Number :
PA1862
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Tyrosine-protein kinase transmembrane receptor ROR1(ROR1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, rat Predicted to work with: mouse
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human ROR1(904-918aa NKSQKPYKIDSKQAS), different from the related rat and mouse sequences by one amino acid.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
ROR1(receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase, receptor-related 1(NTRKR1), Tyrosine-protein kinase transmembrane receptor ROR1, is a member of thereceptor tyrosine kinase-like orphan receptor(ROR) family. NTRKR1 encodes a predicted 937-amino acid protein. A 6-kb NTRKR1 mRNA is expressed strongly in human heart, lung, and kidney, but weakly in the CNS. However, a truncated 2.4-kb mRNA lacking extracellular and transmembrane domains was strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. The protein encoded by this gene is a receptor tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors.
Reference :
1. Reddy, U. R., Phatak, S., Allen, C., Nycum, L. M., Sulman, E. P., White, P. S., Biegel, J. A. Localization of the human Ror1 gene (NTRKR1) to chromosome 1p31-p32 by fluorescence in situ hybridization and somatic cell hybrid analysis.Genomics 41: 283-285, 1997.
Gene Name :
ROR1
Protein Name :
Tyrosine-protein kinase transmembrane receptor ROR1
Gene Full Name :
receptor tyrosine kinase-like orphan receptor 1
Synonyms :
dJ537F10.1 antibody MGC99659 antibody Neurotrophic tyrosine kinase antibody Neurotrophic tyrosine kinase receptor related 1 antibody Neurotrophic tyrosine kinase, receptor related 1 antibody NTRKR1 antibody OTTHUMP00000010573 antibody OTTHUMP00000010574 antibody OTTMUSP00000008344 antibody Receptor tyrosine kinase like orphan receptor 1 antibody receptor-related 1 antibody RGD1559469 antibody ROR 1 antibody ROR1 antibody ROR1_HUMAN antibody RP11 24J23.1 antibody Ttyrosine protein kinase transmembrane receptor ROR1 antibody Tyrosine kinase like orphan receptor 1 antibody Tyrosine protein kinase transmembrane receptor ROR1 antibody Tyrosine-protein kinase transmembrane receptor ROR1 antibody
Uniprot ID :
Q01973
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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