Boster Immunoleader

antibody

Anti-RIP2 Antibody

PA1861

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-RIP2 Antibody

PA1861

Polyclonal

Rabbit IgG polyclonal antibody for Receptor-interacting serine/threonine-protein kinase 2(RIPK2) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human RIP2(495-514aa DIQGEEFAKVIVQKLKDNKQ), different from the related rat and mouse sequences by one amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

RIPK2(Receptor-interacting serine/threonine-protein kinase 2), also known as CARD3, CARDIAK, RICK, RIP2, is an enzyme that in humans is encoded by the RIPK2 gene. It has 540-amino acid protein in length. Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein(RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain(CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappa B and inducer of apoptosis in response to various stimuli, CARDIAK(CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.

1. McCarthy, J. V., Ni, J., Dixit, V. M. RIP2 is a novel NF-kappa-B-activating and cell death-inducing kinase. J. Biol. Chem. 273: 16968-16975, 1998.

RIPK2

Receptor-interacting serine/threonine-protein kinase 2

receptor-interacting serine-threonine kinase 2

CARD 3 antibody CARD carrying kinase antibody CARD containing ICE associated kinase antibody CARD containing IL 1 beta ICE kinase antibody CARD containing IL1 beta ICE kinase antibody CARD containing interleukin 1 beta converting enzyme(ICE) associated kinase antibody CARD containing interleukin 1 beta converting enzyme associated kinase antibody CARD-containing IL-1 beta ICE-kinase antibody CARD-containing interleukin-1 beta-converting enzyme-associated kinase antibody CARD3 antibody CARDIAK antibody CCK antibody CLARP kinase antibody GIG 30 antibody GIG30 antibody Growth inhibiting gene 30 antibody Receptor interacting protein(RIP) like interacting caspase like apoptosis regulatory protein(CLARP) kinase antibody Receptor interacting protein 2 antibody Receptor interacting serine threonine kinase 2 antibody Receptor interacting serine/threonine protein kinase 2 antibody Receptor-interacting protein 2 antibody Receptor-interacting serine/threonine-protein kinase 2 antibody RICK antibody RIP 2 antibody RIP like interacting CLARP kinase antibody RIP-2 antibody RIP-like-interacting CLARP kinase antibody RIPK 2 antibody RIPK2 antibody RIPK2_HUMAN antibody TNFRSF antibody

O43353