product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Fatty Acid Binding Protein 5 Antibody
catalog :
PA1853
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse
application :
western blot, immunohistochemistry - paraffin section
product information
Product Name :
Anti-Fatty Acid Binding Protein 5 Antibody
Catalog Number :
PA1853
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Fatty acid-binding protein, epidermal(FABP5) detection. Tested with WB, IHC-P in Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: rat Predicted to work with: mouse
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Mouse
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the N-terminus of mouse Fatty Acid Binding Protein 5(10-23aa KWRLMESHGFEEYM), different from the related rat sequence by two amino acids.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
FABP5(fatty acid binding protein 5(psoriasis-associated)) is a protein that in humans is encoded by the FABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog. It is a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with molecular weight 15,164. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. It is though that FABPs roles include fatty acid uptake, transport, and metabolism. Kaczocha et al.(2009) identified FABP5 and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.
Reference :
1. Kaczocha, M., Glaser, S. T., Deutsch, D. G.Identification of intracellular carriers for the endocannabinoid anandamide. Proc. Nat. Acad. Sci. 106: 6375-6380, 2009. 2. Madsen, P., Rasmussen, H. H., Leffers, H., Honore, B., Celis, J. E. Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins. J. Invest. Derm. 99: 299-305, 1992.
Gene Name :
FABP5
Protein Name :
Fatty acid-binding protein, epidermal
Gene Full Name :
fatty acid binding protein 5(psoriasis-associated)
Synonyms :
CFABP antibody Cutaneous fatty acid binding protein antibody DA11 antibody Differentiation associated lipid binding protein LP2 antibody E-FABP antibody EFABP antibody Epidermal-type fatty acid-binding protein antibody FABP5 antibody FABP5_HUMAN antibody fatty acid binding protein 5(psoriasis-associated) antibody Fatty acid binding protein epidermal antibody Fatty acid-binding protein 5 antibody Fatty acid-binding protein, epidermal antibody Keratinocyte lipid binding protein antibody KFABP antibody Klbp antibody mal1 antibody PA-FABP antibody PAFABP antibody Psoriasis associated fatty acid binding protein homolog antibody Psoriasis-associated fatty acid-binding protein homolog antibody
Uniprot ID :
Q05816
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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