product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-HSPA2 Antibody
catalog :
PA1814
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
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product information
Product Name :
Anti-HSPA2 Antibody
Catalog Number :
PA1814
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Heat shock-related 70 kDa protein 2(HSPA2) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, mouse, rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA2(580-599aa VINWLDRNQMAEKDEYEHKQ), identical to the related mouse and rat sequences.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
HSPA2(heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that HSPA2 is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2 has less amino acid homology to the other members of the human HSP70 gene family. HSPA2 is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The HSPA2 gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of HSPA2 in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2 may be critical to sperm maturation through its role as a protein chaperone.
Reference :
1. Bonnycastle, L. L. C., Yu, C.-E., Hunt, C. R., Trask, B. J., Clancy, K. P., Weber, J. L., Patterson, D., Schellenberg, G. D. Cloning, sequencing, and mapping of the human chromosome 14 heat shock protein gene (HSPA2). Genomics 23: 85-93, 1994.
2. Dix, D. J., Allen, J. W., Collins, B. W., Mori, C., Nakamura, N., Poorman-Allen, P., Goulding, E. H., Eddy, E. M. Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility. Proc. Nat. Acad. Sci. 93: 3264-3268, 1996.
3. Hunt, C. R., Gasser, D. L., Chaplin, D. D., Pierce, J. C., Kozak, C. A. Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t and Grp78. Genomics 16: 193-198, 1993.
Gene Name :
HSPA2
Protein Name :
Heat shock-related 70 kDa protein 2
Gene Full Name :
heat shock 70kDa protein 2
Synonyms :
70kDa antibody DAQB 147D11.1 001 antibody Hcp70.2 antibody Heat shock 70 kDa protein 2 antibody heat shock 70kDa protein 1A antibody Heat shock protein 2 antibody heat shock protein 70 antibody Heat shock protein 70.2 antibody Heat shock related 70 kDa protein 2 antibody Heat shock-related 70 kDa protein 2 antibody Heat-shock protein, 70-KD, 2 antibody Heat-shock protein, 70-KD, 3 antibody HSP70 2 antibody HSP70 3 antibody Hsp70-2 antibody HSP70-3 antibody HSP70.2 antibody HSP70A2 antibody HSP72 antibody HSP72_HUMAN antibody HSPA2 antibody Hspt70 antibody Hst70 antibody MGC58299 antibody MGC7795 antibody MGC93458 antibody OTTHUMP00000180664 antibody Testis-specific heat shock protein-related antibody XXbac BCX40G17.3 001 antibody
Uniprot ID :
P54652
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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