Anti-Grp75 Antibody | Boster Immunoleader PA1789 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Grp75 Antibody

catalog :

PA1789

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Grp75 Antibody

Catalog Number :

PA1789

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Stress-70 protein, mitochondrial(HSPA9) detection. Tested with WB, IHC-P, IHC-F, ICC in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, Mouse, Rat. No cross reactivity with other proteins.

Applications :

WB,IHC-P,IHC-F,ICC

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat

Immunohistochemistry(Frozen Section) :

Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse

Immunocytochemistry :

Concentration: 0.5-1μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Grp75(591-609aa DTETKMEEFKDQLPADECN), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Background :

HSPA9(heat shock 70kDa protein 9(mortalin)), also known as GRP75, mot-2, mthsp75, PBP74,HSPA9B, MORTALIN or MORTALIN, PERINUCLEAR, is a highly conserved member of the HSP70 family of proteins. It functions as a chaperone in the mitochondria, cytoplasm, and centrosome. The HSPA9 gene is mapped to chromosome 5q31.2 based on an alignment of the HSPA9 sequence with the genomic sequence. Knockdown of HSPA9 in erythroid cultures was associated with an increased number of cells in the G0/G1 phase of the cell cycle and accelerated apoptosis. Knockdown of Hspa9 in mouse bone marrow cells, followed by transplantation into wildtype recipients, also resulted in loss of erythroid cell number. Haploinsufficiency for HSPA9 may contribute to abnormal hematopoiesis in myelodysplastic syndromes with deletions spanning chromosome 5q31.2. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.

Gene Name :

HSPA9

Protein Name :

Stress-70 protein, mitochondrial

Gene Full Name :

heat shock 70kDa protein 9(mortalin)

Synonyms :

75 kDa glucose regulated protein antibody 75 kDa glucose-regulated protein antibody CSA antibody Glucose Regulated Protein antibody Grp 75 antibody GRP-75 antibody GRP75 antibody GRP75_HUMAN antibody Heat shock 70 kDa protein 9 antibody Heat shock 70kD protein 9 antibody heat shock 70kDa protein 9 antibody Heat shock 70kDa protein 9B antibody Heat shock protein 74 kDa A antibody Heat shock protein A antibody Heat shock protein cognate 74 antibody Hsc74 antibody Hsp74 antibody Hsp74a antibody HSPA9 antibody Hspa9a antibody HSPA9B antibody MGC4500 antibody mitochondrial antibody Mortalin 2 antibody Mortalin antibody Mortalin perinuclear antibody Mortalin2 antibody MOT 2 antibody MOT antibody MOT2 antibody Mthsp70 antibody p66 mortalin antibody P66 MOT antibody PBP74 antibody Peptide binding protein 74 antibody Peptide-binding protein 74 antibody Stress 70 protein mitochondrial antibody Stress 70 protein mitochondrial precursor antibody Stress-70 protein antibody

Uniprot ID :

P38646

more info or order :

Boster Immunoleader product webpage