Boster Immunoleader

antibody

Anti-GRO alpha Antibody

PA1760

100 ug/vial

200 USD

polyclonal

rabbit

Anti-GRO alpha Antibody

PA1760

Polyclonal

Rabbit IgG polyclonal antibody for Growth-regulated alpha protein(CXCL1) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human GRO alpha(99-107aa KMLNSDKSN).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

CXCL1(Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROalpha, KC, Neutrophil-activating protein 3(NAP-3) and melanoma growth stimulating activity, alpha(MSGA-alpha). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation,wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated.

1. Anisowicz, A., Zajchowski, D., Stenman, G., Sager, R. Functional diversity of GRO gene expression in human fibroblasts and mammary epithelial cells. Proc. Nat. Acad. Sci. 85: 9645-9649, 1988. 2. Horuk, R., Yansura, D. G., Reilly, D., Spencer, S., Bourell, J., Henzel, W., Rice, G., Unemori, E. Purification, receptor binding analysis, and biological characterization of human melanoma growth stimulating activity (MGSA): evidence for a novel MGSA receptor. J. Biol. Chem. 268: 541-546, 1993. 3. O'Donovan, N., Galvin, M., Morgan, J. G. Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84: 39-42, 1999.

CXCL1

Growth-regulated alpha protein

chemokine(C-X-C motif) ligand 1(melanoma growth stimulating activity, alpha)

C-X-C motif chemokine 1 antibody Chemokine(C X C motif) ligand 1 antibody Chemokine(C-X-C motif) ligand 1(melanoma growth stimulating activity, alpha) antibody chemokine(C-X-C motif) ligand 1 antibody Chemokine ligand 1 antibody CINC-1 antibody Cxcl 1 antibody Cxcl1 antibody Cytokine-induced neutrophil chemoattractant 1 antibody Fibroblast secretory protein antibody Fsp antibody Gro 1 antibody Gro A antibody GRO alpha antibody GRO antibody GRO protein, alpha antibody GRO-alpha(1-73) antibody GRO-alpha(6-73) antibody Gro1 antibody GRO1 oncogene(melanoma growth stimulating activity, alpha) antibody GRO1 oncogene(melanoma growth-stimulating activity) antibody Gro1 oncogene antibody GroA antibody GROA_HUMAN antibody Growth regulated protein alpha antibody Growth regulated protein GRO antibody KC antibody KC chemokine, mouse, homolog of antibody Melanoma growth stimulatory activity alpha antibody Melanoma growth stimulatory activity antibody Melanoma growth stimulatory activity, alpha antibody MGSA a antibody MGSA alpha antibody MGSA antibody MGSA-a antibody N51 antibody NAP 3 antibody NAP-3 antibody NAP3 antibody Neutrophil activating protein 3 antibody Neutrophil-activating protein 3 antibody Platelet-derived growth factor-inducible protein KC antibody Scyb 1 antibody SCYB1 antibody Secretory protein N51 antibody Small inducible cytokine subfamily B, member 1 antibody

P09341