Boster Immunoleader

antibody

Anti-IL2RA Antibody

PA1747

100 ug/vial

200 USD

polyclonal

rabbit

western blot, immunohistochemistry - paraffin section

Anti-IL2RA Antibody

PA1747

Polyclonal

Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit alpha(IL2RA) detection. Tested with WB, IHC-P in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human IL2RA(39-57aa MAYKEGTMLNCECKRGFRR).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

IL2RA(Interleukin 2 receptor, alpha), also called IL2R, IL2R, Alpha Chain or CD25, is a protein that in humans is encoded by the IL2RA gene.The IL2RA gene is mapped on 10p15.1. IL2RA is composed of strand-swapped "sushi-like" domains, unlike the classical cytokine receptor fold. As a result of this domain swap, IL2RA uses a composite surface to dock into a groove on IL2 that also serves as a binding site for antagonist drugs.Homodimeric alpha chains(IL2RA) result in low-affinity receptor, while homodimeric beta(IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Infection by the protozoan Trypanosoma cruzi causes Chagas disease, characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression, becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated.

1. Ansano, M., Toda, M., Sakaguchi, N., Sakaguchi, S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184: 387-396, 1996. 2. Cosman, D., Cerretti, D. P., Larsen, A., Park, L., March, C., Dower, S., Gillis, S., Urdal, D. Cloning, sequence and expression of human interleukin-2 receptor. Nature 312: 768-771, 1984. 3. Hori, S., Nomura, T., Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061, 2003.

IL2RA

Interleukin-2 receptor subunit alpha(IL-2 receptor subunit alpha/IL-2-RA/IL-2R subunit alpha/IL2-RA)

interleukin 2 receptor, alpha

CD25 antibody IDDM10 antibody IL 2 RA antibody IL 2 receptor subunit alpha antibodyIL 2R alpha chain antibody IL 2R subunit alpha antibody IL-2 receptor subunit alpha antibody IL-2-RA antibody IL-2R subunit alpha antibody IL2 RA antibody IL2 Receptor alpha antibody IL2 receptor subunit alpha antibody IL2-RA antibody IL2R alpha chain antibody IL2R antibody IL2R subunit alpha antibody IL2RA antibody IL2RA_HUMAN antibody Interleukin 2 receptor alpha chain antibody interleukin 2 receptor subunit alpha antibody Interleukin 2 receptor, alpha antibody Interleukin-2 receptor subunit alpha antibody Ly 43 antibody Ly43 antibody OTTHUMP00000019030 antibody OTTHUMP00000019031 antibody OTTHUMP00000019032 antibody p55 antibody p55 chain antibody T Cell Growth Factor Receptor antibody TAC antigen antibody TCGFR antibody

P01589