product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-alpha Lactalbumin Antibody
catalog :
PA1708
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-alpha Lactalbumin Antibody
Catalog Number :
PA1708
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Alpha-lactalbumin(LALBA) detection. Tested with WB, IHC-P in Human.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the N-terminus of human alpha Lactalbumin(20-37aa KQFTKCELSQLLKDIDGY).
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
LALBA(lactalbumin, alpha or alpha-lactalbumin) is a protein that in humans is encoded by the LALBA gene. The LALBA gene is mapped on 12q13.11. alpha-Lactalbumin is an important whey protein in cow's milk(1 g/l), and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. alpha-Lactalbumin forms the regulatory subunit of the lactose synthase(LS) heterodimer and beta-1, 4-galactosyltransferase(beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a multimer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of human alpha-lactalbumin that may form in acidic environments such as the stomach, called HAMLET, probably induces apoptosis in tumor and immature cells.
Reference :
1. Bounous, G., Kongshavn, P. A. L., Taveroff, A., Gold, P. Evolutionary traits in human milk proteins. Med. Hypotheses 27: 133-140, 1988.
2. Davies, M. S., West, L. F., Davis, M. B., Povey, S., Craig, R. K. The gene for human alpha-lactalbumin is assigned to chromosome 12q13. Ann. Hum. Genet. 51: 183-188, 1987.
3. Hakansson, A., Zhivotovsky, B., Orrenius, S., Sabharwal, H., Svanborg, C. Apoptosis induced by a human milk protein. Proc. Nat. Acad. Sci. 92: 8064-8068, 1995.
Gene Name :
LALBA
Protein Name :
Alpha-lactalbumin
Gene Full Name :
lactalbumin, alpha-
Synonyms :
a-LACTA antibody alfaLA antibody Alpha-lactalbumin antibody Lactalbumin alpha antibody Lactose synthase B protein antibody LALBA antibody LALBA_HUMAN antibody Lysozyme-like protein 7 antibody LYZL7 antibody MGC138521 antibody MGC138523 antibody
Uniprot ID :
P00709
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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