Anti-APLP2 Antibody | Boster Immunoleader PA1654-1 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-APLP2 Antibody

catalog :

PA1654-1

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-APLP2 Antibody

Catalog Number :

PA1654-1

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Amyloid-like protein 2(APLP2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

WB: The detection limit for APLP2 is approximately 0.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human APLP2(639-656aa EEKVINSKNKVDENMVID), different from the related rat and mouse sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

APLP2(Amyloid beta(A4) precursor-like protein 2), also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.

Reference :

1. Leach, R., Ko, M., Krawetz, S. A. Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization. Cytogenet. Cell Genet. 87: 215-216, 1999. 2. von der Kammer, H., Loffler, C., Hanes, J., Klaudiny, J., Scheit, K. H., Hansmann, I. The gene for the amyloid precursor-like protein APLP2 is assigned to human chromosome 11q23-25. Genomics 10: 308-311, 1994. 3. Leach R, Ko M, Krawetz SA (1999). "Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization". Cytogenet. Cell Genet. 87 (3–4): 215–6.

Gene Name :

APLP2

Protein Name :

Amyloid-like protein 2(APLP-2)

Gene Full Name :

amyloid beta(A4) precursor-like protein 2

Synonyms :

amyloid beta(A4) precursor like protein 2 antibody Amyloid like protein 2 antibody Amyloid precursor protein homolog HSD 2 antibody amyloid precursor protein homolog HSD2 antibody Amyloid protein homolog antibody Amyloid-like protein 2 antibody APLP-2 antibody Aplp2 antibody APLP2_HUMAN antibody APPH antibody APPL2 antibody CDEBP antibody CDEI box binding protein antibody CDEI box-binding protein antibody

Uniprot ID :

Q06481

more info or order :

Boster Immunoleader product webpage