product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Angiotensinogen Antibody
catalog :
PA1643
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse, rat
application :
western blot
more info or order :
product information
Product Name :
Anti-Angiotensinogen Antibody
Catalog Number :
PA1643
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Angiotensinogen(AGT) detection. Tested with WB in Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the N-terminus of mouse Angiotensinogen(25-36aa DRVYIHPFHLLY), identical to the related rat sequence.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
AGT(ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Western blot analysis showed a distinct band of expected size of the angiotensinogen protein(61 kD) in isolated adipocytes. The more pronounced AGT increase in TT subjects resulted in similar plasma renin activity at a lower plasma active renin concentration, with a higher plasma renin activity/active renin ratio.
Reference :
1. Abonia, J. P., Abel, K. J., Eddy, R. L., Elliott, R. W., Chapman, V. M., Shows, T. B., Gross, K. W. Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. Mammalian Genome 4: 25-32, 1993.
2. Arakawa, K., Minohara, A., Yamada, J., Nakamura, M. Enzymatic degradation and electrophoresis of human angiotensin I. Biochim. Biophys. Acta 168: 106-112, 1968.
3. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.
Gene Name :
AGT
Protein Name :
Angiotensinogen
Gene Full Name :
angiotensinogen(serpin peptidase inhibitor, clade A, member 8)
Synonyms :
Aangiotensinogen(serpin peptidase inhibitor clade A member 8) antibody AGT antibody AI265500 antibody Alpha 1 antiproteinase antitrypsin antibody Ang antibody Ang I antibody Ang II antibody Ang III antibody AngII antibody Angiotensin I antibody Angiotensin II antibody Angiotensin III antibody Angiotensin-3 antibody Angiotensinogen(PAT) antibody Angiotensinogen antibody ANGT_HUMAN antibody ANHU antibody ANRT antibody Des-Asp-angiotensin II antibody FLJ92595 antibody FLJ97926 antibody MGC105326 antibody PAT antibody Pre angiotensinogen antibody Serine(or cysteine) proteinase inhibitor antibody Serpin A8 antibody Serpin peptidase inhibitor clade A member 8 antibody SERPINA8 antibody
Uniprot ID :
P11859
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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