product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Kallikrein 11 Antibody
catalog :
PA1631
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-Kallikrein 11 Antibody
Catalog Number :
PA1631
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Kallikrein-11(KLK11) detection. Tested with WB, IHC-P in Human.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 11(233-250aa YTKVCKYVDWIQETMKNN).
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
KLK11(KALLIKREIN 11), also called PRSS20 or TLSP, is a protein that in humans is encoded by the KLK11 gene. KLK11 is a member of the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. The KLK11 gene is mapped to 19q13.41. The KLK11 gene contains 6 exons, the first of which is noncoding. KLK11 shares 48% amino acid sequence identity with mouse neuropsin, 43% identity with both human trypsin-1 and human kallikrein, and 38% identity with the mouse nerve growth factor gamma subunit. Alternate splicing of the KLK11 gene results in two transcript variants encoding two different isoforms which are differentially expressed. Western blot analysis of recombinant KLK11 suggested that the protein is secreted and posttranslationally processed.
Reference :
1. Elliott, M. B., Irwin, D. M., Diamandis, E. P. In silico identification and Bayesian phylogenetic analysis of multiple new mammalian kallikrein gene families. Genomics 88: 591-599, 2006.
2. Gan, L., Lee, I., Smith, R., Argonza-Barrett, R., Lei, H., McCuaig, J., Moss, P., Paeper, B., Wang, K. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. Gene 257: 119-130, 2000.
3. Yoshida S, Taniguchi M, Suemoto T, Oka T, He X, Shiosaka S (Oct 1998). "cDNA cloning and expression of a novel serine protease, TLSP".
Gene Name :
KLK11
Protein Name :
Kallikrein-11(hK11)
Gene Full Name :
kallikrein-related peptidase 11
Synonyms :
Hippostasin antibody hK11 antibody Kallikrein 11 antibody Kallikrein 11 isoform 1 preproprotein antibody Kallikrein 11 isoform 2 precursor antibody Kallikrein 11 precursor antibody Kallikrein related peptidase 11 antibody Kallikrein-11 inactive chain 2 antibody KLK 11 antibody Klk11 antibody KLK11_HUMAN antibody MGC33060 antibody Protease serine 20 trypsin like antibody Protease serine trypsin like antibody PRSS20 antibody Serine protease 20 antibody TLSP antibody Trypsin like protease antibody Trypsin-like protease antibody
Uniprot ID :
Q9UBX7
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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