Boster Immunoleader

antibody

Anti-Integrin alpha E Antibody

PA1622

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse

western blot, immunohistochemistry - paraffin section

Anti-Integrin alpha E Antibody

PA1622

Polyclonal

Rabbit IgG polyclonal antibody for Integrin alpha-E(ITGAE) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha E(1153-1168aa KRKYQQLNLESIRKAQ), different from the related rat and mouse sequences by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

ITGAE(INTEGRIN, ALPHA-E), also known as CD103, is an integrin protein that in human is encoded by the ITGAE gene. The ITGAE gene is mapped to chromosome 17p13 by inclusion within a BAC contig. ITGAE is expressed widely on intraepithelial lymphocyte(IEL) T cells(both alphabeta T cells and gammadelta T cells) and on some peripheral regulatory T cells(Tregs) which is important for decreasing the immune response and appears to play a crucial role in the prevention of autoimmune diseases. ITGAE shares overall homology with other alpha integrins but has a unique 55-amino acid "extra" region located just N-terminal to the I domain that contains 18 consecutive charged residues and a proteolytic cleavage site.

1. Cerf-Bensussan, N., Jarry, A., Brousse, N., Lisowska-Grospierre, B., Guy-Grand, D., Griscelli, C. A monoclonal antibody (HML-1) defining a novel membrane molecular present on human intestinal lymphocytes. Europ. J. Immun. 17: 1279-1285, 1987. 2. Parker, C. M., Cepek, K. L, Russell, G. J., Shaw, S. K., Posnett, D. N., Schwarting, R., Brenner, M. B. A family of beta-7 integrins on human mucosal lymphocytes. Proc. Nat. Acad. Sci. 89: 1924-1928, 1992. 3. Kilshaw PJ, Higgins JM (2002). "Alpha E: no more rejection?".

ITGAE

Integrin alpha-E

integrin, alpha E(antigen CD103, human mucosal lymphocyte antigen 1, alpha polypeptide)

A530055J10 antibody alpha-E1 antibody alpha-M290 antibody aM290 antibody Antigen CD103 antibody CD 103 antibody CD103 antibody CD103 antigen antibody HML 1 antigen antibody HML-1 antigen antibody HML1 antigen antibody Human mucosal lymphocyte antigen 1 antibody Human mucosal lymphocyte antigen 1, alpha subunit antibody Huminae antibody Integrin alpha E heavy chain antibody Integrin alpha E light chain antibody Integrin alpha E, epithelial-associated antibody Integrin alpha E1 antibody Integrin alpha IEL antibody Integrin alpha M290 antibody Integrin alpha-E heavy chain antibody Integrin alpha-IEL antibody Integrin, alpha E(antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) antibody Integrin, alpha E antibody ITAE_HUMAN antibody Itgae antibody MGC141996 antibody MGC183601 antibody Mucosal lymphocyte 1 antigen antibody Mucosal lymphocyte antigen 1 antibody

P38570