Anti-Integrin alpha 3 Antibody | Boster Immunoleader PA1621 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Integrin alpha 3 Antibody

catalog :

PA1621

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot, immunohistochemistry - paraffin section

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product information

Availability :

info changed 20150320

Product Name :

Anti-Integrin alpha 3 Antibody

Catalog Number :

PA1621

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Integrin alpha-3(ITGA3) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3(51-67aa LFGYSVALHRQTERQQR), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

Reference :

1. Akula, S. M., Pramod, N. P., Wang, F.-Z., Chandran, B. Integrin alpha-3/beta-1 (CD 49c/29) is a cellular receptor for Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) entry into the target cells. Cell 108: 407-419, 2002. 2. Dulabon, L., Olson, E. C., Taglienti, M. G., Eisenhuth, S., McGrath, B., Walsh, C. A., Kreidberg, J. A., Anton, E. S. Reelin binds alpha-3-beta-1 integrin and inhibits neuronal migration. Neuron 27: 33-44, 2000. 3. Takada Y, Murphy E, Pil P, Chen C, Ginsberg MH, Hemler ME (Oct 1991). "Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen".

Gene Name :

ITGA3

Protein Name :

Integrin alpha-3

Gene Full Name :

integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor)

Synonyms :

AA407068 antibody Antigen identified by monoclonal antibody J143 antibody CD49 antigen like family member C antibody CD49 antigen-like family member C antibody CD49c antibody CD49c antigen antibody FLJ34631 antibody FLJ34704 antibody FRP 2 antibody FRP-2 antibody FRP2 antibody galactoprotein B3 antibody GAP B3 antibody GAPB3 antibody Integrin alpha 3 antibody Integrin alpha-3 light chain antibody Integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody ITA3_HUMAN antibody ITGA 3 antibody ITGA3 antibody MSK18 antibody URO1 antibody VCA 2 antibody VCA2 antibody Very late activation protein 3 receptor alpha 3 subunit antibody Very Late Activation Protein 3 Receptor Alpha 3 Subunit antibody VL3A antibody VLA 3 alpha chain antibody VLA 3 subunit alpha antibody VLA-3 subunit alpha antibody VLA3 antibody VLA3a antibody

Uniprot ID :

P26006

more info or order :

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