Anti-IL3RA Antibody | Boster Immunoleader PA1617 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IL3RA Antibody

catalog :

PA1617

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-IL3RA Antibody

Catalog Number :

PA1617

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Interleukin-3 receptor subunit alpha(IL3RA) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human IL3RA(135-151aa QYDLYLNVANRRQQYEC).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

IL3RA(INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123(Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.

Reference :

1. Itoh, N., Yonehara, S., Schreurs, J., Gorman, D. M., Maruyama, K., Ishii, A., Yahara, I., Arai, K., Miyajima, A. Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family. Science 247: 324-327, 1990. 2. Kitamura, T., Sato, N., Arai, K., Miyajima, A. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta-subunit for the human IL-3 and GM-CSF receptors. Cell 66: 1165-1174, 1991.

Gene Name :

IL3RA

Protein Name :

Interleukin-3 receptor subunit alpha(IL-3 receptor subunit alpha/IL-3R subunit alpha/IL-3R-alpha/IL-3RA)

Gene Full Name :

interleukin 3 receptor, alpha(low affinity)

Synonyms :

CD123 antibody CD123 antigen antibody hIL 3Ra antibody hIL-3Ra antibody hIL3Ra antibody IL 3 receptor alpha SP2 isoform antibody IL 3R alpha antibody IL-3 receptor subunit alpha antibody IL-3R subunit alpha antibody IL-3R-alpha antibody IL-3RA antibody IL3 Receptor alpha antibody IL3R antibody IL3Ra antibody IL3RA_HUMAN antibody IL3RAX antibody IL3RAY antibody IL3RX antibody IL3RY antibody Interleukin 3 receptor alpha chain antibody Interleukin 3 receptor, alpha(low affinity) antibody Interleukin 3 receptor, alpha antibody Interleukin-3 Receptor alpha antibody Interleukin-3 receptor subunit alpha antibody Interleukin3 receptor antibody Interleukin3 receptor, Y-chromosomal antibody

Uniprot ID :

P26951

more info or order :

Boster Immunoleader product webpage