Boster Immunoleader

antibody

Anti-IL2 Receptor beta Antibody

PA1615

100 ug/vial

200 USD

polyclonal

rabbit

Anti-IL2 Receptor beta Antibody

PA1615

Polyclonal

Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit beta(IL2RB) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor beta(117-135aa RVMAIQDFKPFENLRLMAP).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

IL2RB(INTERLEUKIN 2 RECEPTOR, BETA),also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.

1. Campbell, H. D., Webb, G. C., Kono, T., Taniguchi, T., Ford, J. H., Young, I. G. Assignment of the interleukin-2 receptor beta chain gene (Il-2rb) to band E on mouse chromosome 15. Genomics 12: 179-180, 1992. 2. Dai, H., Wan, N., Zhang, S., Moore, Y., Wan, F., Dai, Z. Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells. J. Immun. 185: 803-807, 2010. 3. Yamashita, Yuki; Kojima Katsuhiko, Tsukahara Tomonori, Agawa Hideyuki, Yamada Koichiro, Amano Yuji, Kurotori Naoki, Tanaka Nobuyuki, Sugamura Kazuo, Takeshita Toshikazu (May. 2008). "Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain". J. Cell. Sci. (England) 121 (Pt 10): 1727–38. doi:10.1242/jcs.024455.

IL2RB

Interleukin-2 receptor subunit beta(IL-2 receptor subunit beta/IL-2R subunit beta/IL-2RB)

interleukin 2 receptor, beta

CD 122 antibody CD122 antibody CD122 antigen antibody High affinity IL 2 receptor beta subunit antibody High affinity IL 2 receptor subunit beta antibody High affinity IL-2 receptor subunit beta antibody High affinity IL2 receptor beta subunit antibody High affinity IL2 receptor subunit beta antibody IL 2 receptor antibody IL-2 receptor subunit beta antibody IL-2R subunit beta antibody IL-2RB antibody IL15RB antibody IL2 R B antibody IL2 RB antibody IL2 receptor antibody IL2RB antibody IL2RB_HUMAN antibody Interleukin 2 receptor beta antibody Interleukin 2 receptor subunit beta antibody Interleukin-2 receptor subunit beta antibody OTTHUMP00000028799 antibody P70 75 antibody P70-75 antibody P7075 antibody p75 antibody

P14784