Boster Immunoleader

antibody

Anti-IKK alpha Antibody

PA1614

100 ug/vial

200 USD

polyclonal

rabbit

Anti-IKK alpha Antibody

PA1614

Polyclonal

Rabbit IgG polyclonal antibody for Inhibitor of nuclear factor kappa-B kinase subunit alpha(CHUK) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human IKK alpha(728-745aa NEEQGNSMMNLDWSWLTE).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

IKBKA(INHIBITOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B CELLS, KINASE OF, ALPHA), also called CHUK, NFKBIKA, IKKA, IKK1, I-KAPPA-B, is a protein kinase that in humans is encoded by the CHUK gene. And it is a member of the protein kinase superfamily. And the protein contains a serine/threonine kinase domain, due to its ubiquitous expression in a broad array of tissues and high degree of conservation across species. By FISH, the IKBKA gene is mapped to chromosome 10q24. Phosphorylation of serine residues on the I-kappa-B proteins by kinases(IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. IKK-alpha is part of the I kappa B kinase complex that plays an important role in regulating the NF-kappa B transcription factor.

1. Mock BA, Connelly MA, McBride OW, Kozak CA, Marcu KB (May 1995). "CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19". 2. Anest, V., Hanson, J. L., Cogswell, P. C., Steinbrecher, K. A., Strahl, B. D., Baldwin, A. S. A nucleosomal function for I-kappa-B kinase-alpha in NF-kappa-B-dependent gene expression. Nature 423: 659-663, 2003. 3. Delhase, M., Hayakawa, M., Chen, Y., Karin, M. Positive and negative regulation of I-kappa-B kinase activity through IKK-beta subunit phosphorylation. Science 284: 309-312, 1999.

CHUK

Inhibitor of nuclear factor kappa-B kinase subunit alpha(I-kappa-B kinase alpha/IKK-A/IKK-alpha/IkBKA/IkappaB kinase)

conserved helix-loop-helix ubiquitous kinase

chuk antibody CHUK1 antibody Conserved Helix Loop Helix Ubiquitous Kinase antibody Conserved helix loop ubiquitous kinase antibody Conserved helix-loop-helix ubiquitous kinase antibody I Kappa B Kinase 1 antibody I Kappa B Kinase Alpha antibody I-kappa-B kinase 1 antibody I-kappa-B kinase alpha antibody IkappaB kinase antibody IkB kinase alpha subunit antibody IKBKA antibody IKK 1 antibody IKK A antibody IKK a kinase antibody IKK-A antibody IKK-alpha antibody IKK1 antibody IKKA antibody IKKA_HUMAN antibody Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells antibody Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit antibody Inhibitor of nuclear factor kappa-B kinase subunit alpha antibody NFKBIKA antibody Nuclear Factor Kappa B Inhibitor Kinase Alpha antibody Nuclear factor NF kappa B inhibitor kinase alpha antibody Nuclear factor NF-kappa-B inhibitor kinase alpha antibody Nuclear factor NFkappaB inhibitor kinase alpha antibody Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor antibody TCF-16 antibody TCF16 antibody Transcription factor 16 antibody

O15111