Anti-INDOL1 Antibody | Boster Immunoleader PA1612 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-INDOL1 Antibody

catalog :

PA1612

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-INDOL1 Antibody

Catalog Number :

PA1612

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Indoleamine 2,3-dioxygenase 2(IDO2) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human INDOL1(1-20aa MLHFHYYDTSNKIMEPHRPN).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

IDO2(Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.

Reference :

1. Ball, H. J., Sanchez-Perez, A., Weiser, S., Austin, C. J. D., Astelbauer, F., Miu, J., McQuillan, J. A., Stocker, R., Jermin, L. S., Hunt, N. H. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene 396: 203-213, 2007. 2. Metz, R., DuHadaway, J. B., Kamasani, U., Laury-Kleintop, L., Muller, A. J., Prendergast, G. C. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res. 67: 7082-7087, 2007.

Gene Name :

IDO2

Protein Name :

ndoleamine 2,3-dioxygenase 2

Gene Full Name :

indoleamine 2,3-dioxygenase 2

Synonyms :

3-dioxygenase 2 antibody 3-dioxygenase-like protein 1 antibody EC 1.13.11. antibody I23O2_HUMAN antibody IDO 2 antibody IDO-2 antibody Ido2 antibody INDOL 1 antibody Indoleamine 2 antibody Indoleamine 2,3 dioxygenase 2 antibody Indoleamine 2,3 dioxygenase like 1 protein antibody Indoleamine 2,3 dioxygenase like protein 1 antibody Indoleamine pyrrole 2,3 dioxygenase like 1 antibody Indoleamine pyrrole 2,3 dioxygenase like protein 1 antibody Indoleamine-pyrrole 2 antibody

Uniprot ID :

Q6ZQW0

more info or order :

Boster Immunoleader product webpage