Anti-HOXA3 Antibody | Boster Immunoleader PA1602 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-HOXA3 Antibody

catalog :

PA1602

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-HOXA3 Antibody

Catalog Number :

PA1602

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Homeobox protein Hox-A3(HOXA3) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human Predicted to work with: mouse, rat

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human HOXA3(427-443aa HHPSQGRIQEAPKLTHL), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

HOXA3(HOMEOBOX A3) is a protein that in humans is encoded by the HOXA3 gene, which is also part of the A cluster on chromosome 7. HOXA3 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA3 protein is able to complement Hoxd3 deficiency when expressed in the context of the Hoxd3 allele.

Reference :

1. Greer, J. M., Puetz, J., Thomas, K. R., Capecchi, M. R. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature 403: 661-665, 2000. 2. McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". 3. Han L, Witmer PD, Casey E, Valle D, Sukumar S (2007). "DNA methylation regulates MicroRNA expression".

Gene Name :

HOXA3

Protein Name :

Homeobox protein Hox-A3

Gene Full Name :

homeobox A3

Synonyms :

Homeo box 1E antibody Homeo box A3 antibody Homeobox 1E antibody Homeobox A3 antibody Homeobox protein HOX A3 antibody Homeobox protein Hox-1E antibody Homeobox protein Hox-A3 antibody Homeobox protein HOXA3 antibody Homeobox1E antibody HomeoboxA3 antibody HOX 1 antibody Hox 1.5 like protein antibody HOX 1E antibody HOX A3 antibody HOX1 antibody Hox1.5 antibody Hox1.5 like protein antibody HOX1E antibody HOXA 3 antibody HOXA3 antibody HXA3_HUMAN antibody MGC10155 antibody

Uniprot ID :

O43365

more info or order :

Boster Immunoleader product webpage