Boster Immunoleader

antibody

Anti-PAK1 Antibody

PA1563

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

info changed 20150508

Anti-PAK1 Antibody

PA1563

Polyclonal

Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PAK 1(PAK1) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human PAK1(1-14aa MSNNGLDIQDKPPA), different from the related mouse and rat sequences by on amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternative transcripts of this gene have been found, but their full-length natures have not yet been determined. The PAK1 gene is mapped to 11q13-q14 by inclusion within a mapped clone.

1. Brown JL, Stowers L, Baer M, Trejo J, Coughlin S, Chant J (Mar 1997). "Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway". Curr Biol 6 (5): 598–605. 2. Bekri S, Adelaide J, Merscher S, Grosgeorge J, Caroli-Bosc F, Perucca-Lostanlen D, Kelley PM, Pebusque MJ, Theillet C, Birnbaum D, Gaudray P (Apr 1998). "Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma". Cytogenet Cell Genet 79 (1–2): 125–31. 3. "Entrez Gene: PAK1 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)". 4. Bekri, S., Adelaide, J., Merscher, S., Grosgeorge, J., Caroli-Bosc, F., Perucca-Lostanlen, D., Kelley, P. M., Pebusque, M.-J., Theillet, C., Birnbaum, D., Gaudray, P. Detailed map of a region commonly amplified at 11q13-q14 in human breast carcinoma. Cytogenet. Cell Genet. 79: 125-131, 1997.

PAK1

Serine/threonine-protein kinase PAK 1

p21 protein(Cdc42/Rac)-activated kinase 1

Alpha PAK antibody Alpha-PAK antibody MGC130000 antibody MGC130001 antibody p21 activated kinase 1 antibody p21 protein(Cdc42/Rac) activated kinase 1 antibody p21-activated kinase 1 antibody p21/Cdc42/Rac1 activated kinase 1(yeast Ste20 related) antibody p21/Cdc42/Rac1 activated kinase 1 antibody p21/Cdc42/Rac1-activated kinase 1(STE20 homolog, yeast) antibody p65 PAK antibody p65-PAK antibody PAK alpha antibody PAK-1 antibody Pak1 antibody PAK1_HUMAN antibody Paka antibody PAKalpha antibody Protein kinase MUK2 antibody Rac/p21-activated kinase antibody Serine/threonine-protein kinase PAK 1 antibody STE20 homolog(yeast) antibody STE20 homolog yeast antibody

Q13153