product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-LIF Antibody
catalog :
PA1562
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse, rat
application :
western blot
product information
Product Name :
Anti-LIF Antibody
Catalog Number :
PA1562
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Leukemia inhibitory factor(LIF) detection. Tested with WB in Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of mouse LIF(175-194aa DKEAFQRKKLGCQLLGTYKQ), identical to the related rat sequence.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. LIF could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2.
Reference :
1. Bamberger, A.-M., Jenatschke, S., Schulte, H. M., Loning, T., Bamberger, C. M. Leukemia inhibitory factor (LIF) stimulates the human HLA-G promoter in JEG3 choriocarcinoma cells. J. Clin. Endocr. Metab. 85: 3932-3936, 2000. 2. Sutherland, G. R., Baker, E., Hyland, V. J., Callen, D. F., Stahl, J., Gough, N. M. The gene for human leukemia inhibitory factor (LIF) maps to 22q12. Leukemia 3: 9-13, 1989.
Gene Name :
LIF
Protein Name :
Leukemia inhibitory factor(LIF)
Gene Full Name :
leukemia inhibitory factor
Synonyms :
CDF antibody Cholinergic Differentiation Factor antibody D factor antibody DIA antibody Differentiation inducing factor antibody differentiation inhibitory activity antibody Differentiation stimulating factor antibody Differentiation-stimulating factor antibody Emfilermin antibody Hepatocyte stimulating factor III antibody HILDA antibody Human interleukin in DA cells antibody Leukemia inhibitory factor antibody LIF antibody Lif antibody LIF_HUMAN antibody Melanoma derived LPL inhibitor antibody Melanoma-derived LPL inhibitor antibody MLPLI antibody
Uniprot ID :
P09056
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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