Anti-EDA Antibody | Boster Immunoleader PA1561 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-EDA Antibody

catalog :

PA1561

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

publications citing this reagent :

Cai Q, Yao Z, Li H. Catalpol promotes oligodendrocyte survival and oligodendrocyte progenitor differentiation via the Akt signaling pathway in rats with chronic cerebral hypoperfusion. Brain Res. 2014;1560:27-35 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-EDA Antibody

Catalog Number :

PA1561

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Ectodysplasin-A(EDA) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human Predicted to work with: mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human; Predicted Species: Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human EDA(254-269aa HLQGQGSAIQVKNDLS), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Anhidrotic ectodermal dysplasia(EDA) is an X-linked recessive disorder which affects ectodermal structures. Ectodysplasin-A, the protein encoded by the EDA gene, is a member of the tumor necrosis factor ligand superfamily that forms a collagen triple helix, suggesting functions in signal transduction and cell adhesion. Wnt signaling does control EDA gene expression, but ectodysplasin-A does not feedback on the Wnt pathway.

Reference :

1. Bayes, M., Hartung, A. J., Ezer, S., Pispa, J., Thesleff, I., Srivastava, A. K., Kere, J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum. Molec. Genet. 7: 1661-1669, 1998. 2. Durmowicz, M. C., Cui, C.-Y., Schlessinger, D. The EDA gene is a target of, but does not regulate Wnt signaling. Gene 285: 203-211, 2002.

Gene Name :

EDA

Protein Name :

Ectodysplasin-A

Gene Full Name :

ectodysplasin A

Synonyms :

Ectodermal dysplasia 1, anhidrotic antibody Ectodermal dysplasia protein antibody Ectodermal dysplasia, anhidrotic(hypohydrotic) antibody Ectodysplasin A antibody Ectodysplasin A, membrane form antibody Ectodysplasin A, secreted form antibody ECTODYSPLASIN A1 ISOFORM antibody ECTODYSPLASIN A2 ISOFORM antibody ECTODYSPLASIN antibody Ectodysplasin-A antibody ED1 A1 antibody ED1 A2 antibody ED1 antibody ED1 GENE antibody Eda A1 antibody Eda A2 antibody eda antibody EDA protein antibody EDA protein homolog antibody EDA_HUMAN antibody EDA1 antibody EDA1 GENE antibody EDA2 antibody HED antibody ODT1 antibody Oligodontia 1 antibody secreted form antibody STHAGX1 antibody Ta antibody Tabby antibody Tabby protein antibody X linked anhidroitic ectodermal dysplasia protein antibody XHED antibody XLHED antibody

Uniprot ID :

Q92838

more info or order :

Boster Immunoleader product webpage