Anti-DAP Kinase 2 Antibody | Boster Immunoleader PA1558 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-DAP Kinase 2 Antibody

catalog :

PA1558

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-DAP Kinase 2 Antibody

Catalog Number :

PA1558

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Death-associated protein kinase 2(DAPK2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human DAP Kinase 2(289-308aa DNQQAMVRRESVVNLENFRK), different from the related mouse and rat sequences by two amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Death-associated protein kinase 2 is an enzyme that in humans is encoded by the DAPK2 gene. This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1(DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. The DAPK2 mRNA may undergo alternative splicing to produce a DAPK3-like encoding transcript.

Reference :

1. Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ, Jenkins NA, Akira S (Jun 1999). "Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity". Oncogene 18 (23): 3471–80. 2. "Entrez Gene: DAPK2 death-associated protein kinase 2". 3. "New Modularity of DAP-Kinases: Alternative Splicing of the DRP-1 Gene Produces a ZIPk-Like Isoform".

Gene Name :

DAPK2

Protein Name :

Death-associated protein kinase 2(DAP kinase 2)

Gene Full Name :

death-associated protein kinase 2

Synonyms :

DAK 2 antibody DAK2 antibody DAP kinase 2 antibody DAP kinase related protein 1 antibody DAP kinase related protein 1 beta isoform antibody DAP-kinase-related protein 1 antibody DAPK 2 antibody DAPK2 antibody DAPK2_HUMAN antibody Death associated protein kinase 2 antibody Death-associated protein kinase 2 antibody DRP 1 antibody DRP-1 antibody DRP1 antibody MGC119312 antibody

Uniprot ID :

Q9UIK4

more info or order :

Boster Immunoleader product webpage