Anti-Stra8 Antibody | Boster Immunoleader PA1528 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Stra8 Antibody

catalog :

PA1528

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Stra8 Antibody

Catalog Number :

PA1528

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Protein Stra8(STRA8) detection. Tested with WB in Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of rat Stra8(341-355aa DDDVMLLKCLETFDD), different from the related mouse sequence by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid(RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

Reference :

1. Anderson, E. L., Baltus, A. E., Roepers-Gajadien, H. L., Hassold, T. J., de Rooij, D. G., van Pelt, A. M. M., Page, D. C.Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.Proc. Nat. Acad. Sci. 105: 14976-14980, 2008. 2. Miyamoto, T., Sengoku, K., Takuma, N., Hasuike, S., Hayashi, H., Yamauchi, T., Yamashita, T., Ishikawa, M.Isolation and expression analysis of the testis-specific gene, STRA8, stimulated by retinoic acid gene 8.J. Assisted Reprod. Genet. 19: 531-535, 2002.

Gene Name :

STRA8

Protein Name :

Protein Stra8

Gene Full Name :

stimulated by retinoic acid gene 8 homolog(mouse)

Synonyms :

stimulated by retinoic acid 8 homolog antibody Stimulated by retinoic acid Gene 8 antibody stimulated by retinoic acid gene 8 homolog antibody Stimulated by retinoic acid gene 8 protein homolog antibody STRA 8 antibody STRA8 antibody STRA8_HUMAN antibody

Uniprot ID :

D4ADQ4

more info or order :

Boster Immunoleader product webpage