Anti-FGFR1 Antibody | Boster Immunoleader PA1477 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-FGFR1 Antibody

catalog :

PA1477

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

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product information

Product Name :

Anti-FGFR1 Antibody

Catalog Number :

PA1477

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Fibroblast growth factor receptor 1(FGFR1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human FGFR1(806-822aa CLPRHPAQLANCGLKRR), different from the related mouse sequence by two amino acids and rat sequence by three amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

FGFR1, Fibroblast growth factor receptor 1, also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2/Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. The FGFR1 gene is localized to 8p12-p11.2 by in situ hybridization. FGFR1 is essential for the normal formation of the organ of Corti and that phenotype severity observed in FGFR1 mutants is dependent on the dose of FGFR1.Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome 2.

Reference :

1. Pirvola, U., Ylikoski, J., Trokovic, R., Hebert, J. M., McConnell, S. K., Partanen, J. FGFR1 is required for the development of the auditory sensory epithelium. 2. Roscioli, T., Flanagan, S., Kumar, P., Masel, J., Gattas, M., Hyland, V. J., Glass, I. A.Clinical findings in a patient with FGFR1 P252R mutation and comparison with the literature.Am. J. Med. Genet. 93: 22-28, 2000. 3. Ruta, M., Howk, R., Ricca, G., Drohan, W., Zabelshansky, M., Laureys, G., Barton, D. E., Francke, U., Schlessinger, J., Givol, D.A novel protein tyrosine kinase gene whose expression is modulated during endothelial cell differentiation.Oncogene 3: 9-15, 1988.

Gene Name :

FGFR1

Protein Name :

Fibroblast growth factor receptor 1(FGFR-1/bFGF-R-1)

Gene Full Name :

fibroblast growth factor receptor 1

Synonyms :

Basic fibroblast growth factor receptor 1 antibody bFGF R antibody bFGF-R-1 antibody BFGFR antibody C FGR antibody CD 331 antibody CD331 antibody CD331 antigen antibody CEK antibody FGFBR antibody FGFR 1 antibody FGFR-1 antibody FGFR1 antibody FGFR1_HUMAN antibody Fibroblast growth factor receptor 1 antibody FLG antibody FLG protein antibody FLJ14326 antibody FLT 2 antibody FLT-2 antibody FLT2 antibody FMS like tyrosine kinase 2 antibody Fms like tyrosine kinase 2 antibody Fms related tyrosine kinase 2 antibody Fms related tyrosine kinase 2 Pfeiffer syndrome antibody Fms-like tyrosine kinase 2 antibody H2 antibody H3 antibody H4 antibody H5 antibody HBGFR antibody Heparin binding growth factor receptor antibody Hydroxyaryl protein kinase antibody KAL 2 antibody KAL2 antibody MFR antibody N SAM antibody N sam tyrosine kinase antibody Protein tyrosine kinase antibody Proto-oncogene c-Fgr antibody Tyrosylprotein kinase antibody

Uniprot ID :

P11362

more info or order :

Boster Immunoleader product webpage