Boster Immunoleader

antibody

Anti-MMP7 Antibody

PA1471

100 ug/vial

200 USD

polyclonal

rabbit

mouse, rat

western blot, immunohistochemistry - paraffin section

Anti-MMP7 Antibody

PA1471

Polyclonal

Rabbit IgG polyclonal antibody for Matrilysin(MMP7) detection. Tested with WB, IHC-P in Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: mouse, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of mouse MMP7(236-252aa YQRDYSEDFSLTKDDIA), different from the related rat sequence by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

MMP7, matrix metalloproteinase-7, is an enzyme that in humans is encoded by the MMP7 gene. The MMP7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase. By Southern and PCR analysis of 2 different panels of somatic cell hybrids and by isotopic in situ hybridization, the MMP7 gene is mapped to 11q21-q22. It is a member of matrix metalloproteinase family. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.

1. Crawford, H. C., Scoggins, C. R., Washington, M. K., Matrisian, L. M., Leach, S. D.Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas.J. Clin. Invest. 109: 1437-1444, 2002. 2. Knox, J. D., Boreham, D. R., Walker, J.-A., Morrison, D. P., Matrisian, L. M., Nagle, R. B., Bowden, G. T.Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21-q22.Cytogenet. Cell Genet. 72: 179-182, 1996. 3. Muller, D., Quantin, B., Gesnel, M.-C., Millon-Collard, R., Abecassis, J., Breathnach, R.The collagenase gene family in humans consists of at least four members.Biochem. J. 253: 187-192, 1988.

MMP7

Matrilysin

matrix metallopeptidase 7(matrilysin, uterine)

Matrilysin antibody Matrilysin uterine antibody Matrin antibody Matrix Metalloproteinase 7 antibody Matrix metalloproteinase-7 antibody MMP 7 antibody MMP-7 antibody MMP7 antibody MMP7_HUMAN antibody MPSL1 antibody PUMP 1 antibody Pump 1 protease antibody Pump-1 protease antibody PUMP1 antibody Uterine Matrilysin antibody Uterine metalloproteinase antibody

Q10738