Anti-IL23 P19 Antibody | Boster Immunoleader PA1470 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IL23 P19 Antibody

catalog :

PA1470

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-IL23 P19 Antibody

Catalog Number :

PA1470

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Interleukin-23 subunit alpha(IL23A) detection. Tested with WB in Mouse.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of mouse IL23 P19(29-48aa DWAQCQQLSRNLCMLAWNAH), different from the related rat sequence by two amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

IL-23, Interleukin-23, also known as Interleukin-23 subunit alphainin(IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19(the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.

Reference :

1. Hu, W., Dehmel, T., Pirhonen, J., Hartung, H.-P., Kieseier, B. C.Interleukin 23 in acute inflammatory demyelination of the peripheral nerve.Arch. Neurol. 63: 858-864, 2006. 2. Kullberg, M. C., Jankovic, D., Feng, C. G., Hue, S., Gorelick, P. L., McKenzie, B. S., Cua, D. J., Powrie, F., Cheever, A. W., Maloy, K. J., Sher, A.IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.J. Exp. Med. 203: 2485-2494, 2006. 3. Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F., Yu, N., Wang, J., Singh, K., Zonin, F., Vaisberg, E., and 13 others.Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.Immunity 13: 715-725, 2000.

Gene Name :

IL23A

Protein Name :

Interleukin-23 subunit alpha(IL-23 subunit alpha/IL-23-A)

Gene Full Name :

interleukin 23, alpha subunit p19

Synonyms :

alpha subunit P19 antibody IL-23 subunit alpha antibody IL-23-A antibody IL-23p19 antibody IL23 antibody IL23 P 19 antibody IL23A antibody IL23A_HUMAN antibody IL23P19 antibody interleukin 23 alpha subunit p19 antibody interleukin 23 P19 subunit antibody Interleukin-23 subunit alpha antibody Interleukin-23 subunit p19 antibody JKA3 induced upon T cell activation antibody MGC79388 antibody P19 antibody SGRF antibody

Uniprot ID :

Q9EQ14

more info or order :

Boster Immunoleader product webpage