product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Eotaxin 3 Antibody
catalog :
PA1451
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot
product information
Product Name :
Anti-Eotaxin 3 Antibody
Catalog Number :
PA1451
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for C-C motif chemokine 26(CCL26) detection. Tested with WB in Human.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human Eotaxin 3(73-94aa CTHPRKKWVQKYISLLKTPKQL).
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine(C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
Reference :
1. Guo, R.-F., Ward, P. A., Hu, S.-M., McDuffie, J. E., Huber-Lang, M., Shi, M. M.Molecular cloning and characterization of a novel human CC chemokine, SCYA26.Genomics 58: 313-317, 1999. 2. Kitaura, M., Suzuki, N., Imai, T., Takagi, S., Suzuki, R., Nakajima, T., Hirai, K., Nomiyama, H., Yoshie, O.Molecular cloning of a novel human CC chemokine (eotaxin-3) that is a functional ligand of CC chemokine receptor 3.J. Biol. Chem. 274: 27975-27980, 1999. 3. Nakayama, T., Watanabe, Y., Oiso, N., Higuchi, T., Shigeta, A., Mizuguchi, N., Katou, F., Hashimoto, K., Kawada, A., Yoshie, O.Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.J. Immun. 185: 6472-6479, 2010.
Gene Name :
CCL26
Protein Name :
C-C motif chemokine 26
Gene Full Name :
chemokine(C-C motif) ligand 26
Synonyms :
C-C motif chemokine 26 antibody CC chemokine IMAC antibody CCL 26 antibody CCL26 antibody CCL26_HUMAN antibody Chemokine(C C motif) ligand 26 antibody chemokine N1 antibody Eotaxin-3 antibody IMAC antibody Macrophage inflammatory protein 4-alpha antibody MIP 4a antibody MIP 4alpha antibody MIP-4-alpha antibody MIP4a antibody MIP4alpha antibody SCYA 26 antibody SCYA26 antibody Small inducible cytokine A26 antibody Small inducible cytokine subfamily A(Cys Cys) member 26 antibody Small inducible cytokine subfamily A member 26 antibody Small-inducible cytokine A26 antibody Thymic stroma chemokine 1 antibody Thymic stroma chemokine-1 antibody TSC 1 antibody TSC-1 antibody TSC1 antibody
Uniprot ID :
Q9Y258
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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